4D Digital Subtraction Angiography for the Temporal Flow Visualization of Intracranial Aneurysms and Vascular Malformations

Kato, Naoki; Yuki, Ichiro; Hataoka, Shunsuke; Dahmani, Chihebeddine; Otani, Katharina; Abe, Yukiko; Kakizaki, Shota; Nagayama, Gota; Maruyama, Fumiaki; Ikemura, Ayako; Kan, Issei; Kodama, Takahide; Ishibashi, Toshiyuki; Murayama, Yuichi

doi:10.1016/j.jstrokecerebrovasdis.2020.105327

Cited by 16 publications

(11 citation statements)

References 12 publications

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“…Several groups have propagated advanced DSA imaging including visualization of flow fields [7,23,39]. This method appears to be consistent with computational fluid dynamics in evaluating inflow direction and recirculation in aneurysms.…”

Section: Advanced Dsamentioning

confidence: 77%

Recent progress understanding pathophysiology and genesis of brain AVM—a narrative review

Steiger

2021

Neurosurg Rev

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Considerable progress has been made over the past years to better understand the genetic nature and pathophysiology of brain AVM. For the actual review, a PubMed search was carried out regarding the embryology, inflammation, advanced imaging, and fluid dynamical modeling of brain AVM. Whole-genome sequencing clarified the genetic origin of sporadic and familial AVM to a large degree, although some open questions remain. Advanced MRI and DSA techniques allow for better segmentation of feeding arteries, nidus, and draining veins, as well as the deduction of hemodynamic parameters such as flow and pressure in the individual AVM compartments. Nonetheless, complete modeling of the intranidal flow structure by computed fluid dynamics (CFD) is not possible so far. Substantial progress has been made towards understanding the embryology of brain AVM. In contrast to arterial aneurysms, complete modeling of the intranidal flow and a thorough understanding of the mechanical properties of the AVM nidus are still lacking at the present time.

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Section: Advanced Dsamentioning

confidence: 77%

Recent progress understanding pathophysiology and genesis of brain AVM—a narrative review

Steiger

2021

Neurosurg Rev

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“…Vanrossomme et al reviewed several studies which successfully detected and quantified IA wall deformation between different frames with high spatial and temporal resolutions [35–165 ms and 0.2 mm] ( 52 ). Concerning hemodynamics, 4D-DSA applications have mostly been studied in arteriovenous malformations ( 50 ) and only one study assessed qualitatively the capacity of this imaging to detect IA flow pattern [excellent visualization in 27.7% of IA and fair visualization in 72.3% of IA] ( 53 ). Additionally, Lang et al demonstrated that 4D-DSA is as reliable as 3DRA for CFD analysis as there is no significant differences in the flow velocity or WSS calculated ( 54 ).…”

Section: Hemodynamic Imagingmentioning

confidence: 99%

Imaging Modalities for Intracranial Aneurysm: More Than Meets the Eye

Maupu

Lebas

Boulaftali

2022

Front. Cardiovasc. Med.

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Intracranial aneurysms (IA) are often asymptomatic and have a prevalence of 3 to 5% in the adult population. The risk of IA rupture is low, however when it occurs half of the patients dies from subarachnoid hemorrhage (SAH). To avoid this fatal evolution, the main treatment is an invasive surgical procedure, which is considered to be at high risk of rupture. This risk score of IA rupture is evaluated mainly according to its size and location. Therefore, angiography and anatomic imaging of the intracranial aneurysm are crucial for its diagnosis. Moreover, it has become obvious in recent years that several other factors are implied in this complication, such as the blood flow complexity or inflammation. These recent findings lead to the development of new IA imaging tools such as vessel wall imaging, 4D-MRI, or molecular MRI to visualize inflammation at the site of IA in human and animal models. In this review, we will summarize IA imaging techniques used for the patients and those currently in development.

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“…104 Further extensions of the technique, including tracking the time-varying contrast density due to variable dilution over the cardiac cycle, are being explored to provide quantitative estimates of vascular flow. [105][106][107] 4.3 Motion-Compensated Reconstruction from Single-Sweep Acquisitions…”

Section: D Digital Subtraction Angiographymentioning

confidence: 99%

Flat-panel conebeam CT in the clinic: history and current state

et al. 2021

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. Research into conebeam CT concepts began as soon as the first clinical single-slice CT scanner was conceived. Early implementations of conebeam CT in the 1980s focused on high-contrast applications where concurrent high resolution ( ), for visualization of small contrast-filled vessels, bones, or teeth, was an imaging requirement that could not be met by the contemporaneous CT scanners. However, the use of nonlinear imagers, e.g., x-ray image intensifiers, limited the clinical utility of the earliest diagnostic conebeam CT systems. The development of consumer-electronics large-area displays provided a technical foundation that was leveraged in the 1990s to first produce large-area digital x-ray detectors for use in radiography and then compact flat panels suitable for high-resolution and high-frame-rate conebeam CT. In this review, we show the concurrent evolution of digital flat panel (DFP) technology and clinical conebeam CT. We give a brief summary of conebeam CT reconstruction, followed by a brief review of the correction approaches for DFP-specific artifacts. The historical development and current status of flat-panel conebeam CT in four clinical areas—breast, fixed C-arm, image-guided radiation therapy, and extremity/head—is presented. Advances in DFP technology over the past two decades have led to improved visualization of high-contrast, high-resolution clinical tasks, and image quality now approaches the soft-tissue contrast resolution that is the standard in clinical CT. Future technical developments in DFPs will enable an even broader range of clinical applications; research in the arena of flat-panel CT shows no signs of slowing down.

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4D Digital Subtraction Angiography for the Temporal Flow Visualization of Intracranial Aneurysms and Vascular Malformations

Cited by 16 publications

References 12 publications

Recent progress understanding pathophysiology and genesis of brain AVM—a narrative review

Recent progress understanding pathophysiology and genesis of brain AVM—a narrative review

Imaging Modalities for Intracranial Aneurysm: More Than Meets the Eye

Flat-panel conebeam CT in the clinic: history and current state

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