“…[8][9][10] Other cerebral arteries, embryologically and functionally related to the ophthalmic artery, also demonstrated lower flow resistance in the second trimester of pregnancy among women who were to develop pre-eclampsia. 13,18 In the present study, we describe the range of values of ophthalmic artery Doppler variables in the first trimester of normal pregnancy. To our knowledge, this is the first study to provide a normal reference range for Doppler variables of this vessel in early pregnancy.…”