852 Elastography in the Detection of Prostate Cancer

Giurgiu, C.; Manea, C.N.; Feciche, Bogdan; Crişan, Nicolae; Dudea, Sorin M; Coman, Ioan

doi:10.1016/j.juro.2011.02.673

Cited by 17 publications

(22 citation statements)

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“…In the process of recognizing and selecting associated studies with 11C-choline PET/CT [5,[8][9][10], 18F-FCH PET/ CT [20,44,[49][50][51][52][53][54][55][56][57][58][59][60][61], 11C-acetate PET/CT [7,13,14,62,63], 18F-FDG PET/CT [64][65][66][67][68], TRTE [11,12,[69][70][71][72][73][74][75][76][77][78][79][80][81][82][83][84][85][86][87][88], and SWE [3,…”

Section: Identification Of the Studiesmentioning

confidence: 99%

Comparison of meta-analyses among elastosonography (ES) and positron emission tomography/computed tomography (PET/CT) imaging techniques in the application of prostate cancer diagnosis

et al. 2015

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The early diagnosis of prostate cancer (PCa) appears to be of vital significance for the provision of appropriate treatment programs. Even though several sophisticated imaging techniques such as positron emission tomography/computed tomography (PET/CT) and elastosonography (ES) have already been developed for PCa diagnosis, the diagnostic accuracy of these imaging techniques is still controversial to some extent. Therefore, a comprehensive meta-analysis in this study was performed to compare the accuracy of various diagnostic imaging methods for PCa, including 11C-choline PET/CT, 11C-acetate PET/CT, 18F-fluorocholine PET/CT, 18F-fluoroglucose PET/CT, transrectal real-time elastosonography (TRTE), and shear-wave elastosonography (SWE). The eligible studies were identified through systematical searching for the literature in electronic databases including PubMed, Cochrane, and Web of Science. On the basis of the fixed-effects model, the pooled sensitivity (SEN), specificity (SPE), and area under the receiver operating characteristics curve (AUC) were calculated to estimate the diagnostic accuracy of 11C-choline PET/CT, 11C-acetate PET/CT, 18F-fluorocholine (FCH) PET/CT, 18F-fluoroglucose (FDG) PET/CT, TRTE, and SWE. All the statistical analyses were conducted with R language Software. The present meta-analysis incorporating a total of 82 studies demonstrated that the pooled sensitivity of the six imaging techniques were sorted as follows: SWE > 18F-FCH PET/CT > 11C-choline PET/CT > TRTE > 11C-acetate PET/CT > 18F-FDG PET/CT; the pooled specificity were also compared: SWE > 18F-FCH PET/CT > 11C-choline PET/CT > TRTE > 18F-FDG PET/CT > 11C-acetate PET/CT; finally, the pooled diagnostic accuracy of the six imaging techniques based on AUC were ranked as below: SWE > 18F-FCH PET/CT > 11C-choline PET/CT > TRTE > 11C-acetate PET/CT > 18F-FDG PET/CT. SWE and 18F-FCH PET/CT imaging could offer more assistance in the early diagnosis of PCa than any other studied imaging techniques. However, the diagnostic ranking of the six imaging techniques might not be applicable to the clinical phase due to the shortage of stratified analysis.

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Section: Identification Of the Studiesmentioning

confidence: 99%

Comparison of meta-analyses among elastosonography (ES) and positron emission tomography/computed tomography (PET/CT) imaging techniques in the application of prostate cancer diagnosis

et al. 2015

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“…In prostate cancer, elastography has been demonstrated to be superior to transrectal EUS alone,57 and it improves the specificity of prostate biopsies by highlighting areas highly suspected of malignancy 58. The sensitivity of transrectal elastography in the diagnosis of prostate cancer ranges from 68% to 92%, and its specificity, from 62% to 87%, in patients clinically suspected of prostate cancer 57585960…”

Section: Clinical Applications Of Eus-elastographymentioning

confidence: 99%

Endoscopic ultrasound elastography

Iglesias‐García

Lindkvist

Lariño‐Noia

et al. 2012

Endosopic Ultrasound

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Endoscopic ultrasound (EUS) is a reference technique for diagnosing and staging several different diseases. EUS-guided biopsies and fine needle aspirations are used to improve diagnostic performance of cases where a definitive diagnosis cannot be obtained through conventional EUS. However, EUS-guided tissue sampling requires experience and is associated with a low but not negligible risk of complications. EUS elastography is a non-invasive method that can be used in combination with conventional EUS and has the potential for improving the diagnostic accuracy and reducing the need for EUS-guided tissue sampling in several situations. Elastography measures tissue stiffness by evaluating changes in the EUS image before and after the application of slight pressure to the target tissue by the ultrasonography probe. Pathologic processes such as cancerization and fibrosis alter tissue elasticity and therefore induce changes in elastographic appearance. Qualitative elastography depicts tissue stiffness using different colors, whereas quantitative elastography renders numerical results expressed as a strain ratio or hue histogram mean. EUS elastography has been proven to differentiate between benign and malignant solid pancreatic masses, as well as between benign and malignant lymph nodes with a high accuracy. Studies have also demonstrated that the early changes of chronic pancreatitis can be distinguished from normal pancreatic tissues under EUS elastography. In this article, we review the technical aspects and current clinical applications of qualitative and quantitative EUS elastography and emphasize the potential additional indications that need to be evaluated in future clinical studies.

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“…Elastography Elastography allows the assessment of prostate tissue rigidity and the differentiation between soft and hard areas inside the prostate [31,32]. A harder area is the result of an increased cellularity, microvessels, and collagen deposits [33].…”

Section: New Ultrasound Techniquesmentioning

confidence: 99%

Prostate ultrasound: back in business!

et al. 2017

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The use of grey scale prostate ultrasound decreased after the implementation of magnetic resonance imaging (MRI) for the diagnosis and evaluation of prostate cancer. The new developments, such as multiparametric ultrasound and MRI-ultrasound fusion technology, renewed the interest for this imaging method in the assessment of prostate cancer. The purpose of this paper was to review the current role of prostate ultrasound in the setting of these new applications. A thorough reevaluation of the selection criteria of the patients is required to assess which patients would benefit from multiparametric ultrasound, who wouldbenefit from multiparametric MRI or the combination of both to assist prostate biopsy in order to ensure the balance between overdiagnosis and underdiagnosis of prostate cancer.

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852 Elastography in the Detection of Prostate Cancer

Cited by 17 publications

References 0 publications

Comparison of meta-analyses among elastosonography (ES) and positron emission tomography/computed tomography (PET/CT) imaging techniques in the application of prostate cancer diagnosis

Comparison of meta-analyses among elastosonography (ES) and positron emission tomography/computed tomography (PET/CT) imaging techniques in the application of prostate cancer diagnosis

Endoscopic ultrasound elastography

Prostate ultrasound: back in business!

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