99m-Technetium sestamibi uptake in a gastric schwannoma

Shawgi, Mohamed; Ali, Tamir; Scott, Matthew; Petrides, George

doi:10.4103/1450-1147.222292

Cited by 3 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Outside the neck, uptake of 99m Tc-sestamibi in schwannomas has already been described as a rare finding in the head ( 2 ), and to some extent it has been shown to be an effective radionuclide in the localization of primary and metastatic brain tumors and acoustic schwannomas ( 99m Tc-sestamibi brain SPECT of cerebellopontine angle tumors). It has also been reported as an incidental finding, identifying a gastric schwannoma in a patient investigated for primary hyperparathyroidism ( 23 ).…”

Section: Discussionmentioning

confidence: 96%

Esophageal schwannoma mimicking non-functional parathyroid adenoma on 99mTc-sestamibi imaging: a case report

Fiore,

Gombert,

La Rosa

et al. 2024

Front. Endocrinol.

View full text Add to dashboard Cite

Technetium-99m sestamibi single-photon emission computed tomography/computed tomography (99mTc-sestamibi SPECT/CT) is a mainstay of the pre-operative localization of parathyroid lesions. We report here the case of a 30 year-old woman with a fortuitously discovered 2 cm cervical mass for which a parathyroid origin was originally suspected due to its retro-thyroidal localization and a personal history of nephrolithiasis. Normal serum calcium and parathyroid hormone (PTH) levels excluded primary hyperparathyroidism, raising suspicion of a non-functional parathyroid adenoma, and SPECT/CT imaging showed that the mass was 99mTc-sestamibi-avid. Fine-needle aspiration (FNA) was performed; cytology was non-diagnostic but the needle washout was negative for thyroglobulin, calcitonin and PTH, arguing against a thyroidal or parathyroidal origin of the mass. Core needle biopsy revealed a schwannoma, ostensibly originating from the recurrent laryngeal nerve; upon surgical resection, it was finally found to arise from the esophageal submucosa. This case illustrates the fact that endocrinologists, radiologists, nuclear medicine, head and neck, and other specialists investigating patients with cervical masses should be aware that schwannomas need to be considered in the differential diagnosis of focal 99mTc-sestamibi uptake in the neck region.

show abstract

Section: Discussionmentioning

confidence: 96%

Esophageal schwannoma mimicking non-functional parathyroid adenoma on 99mTc-sestamibi imaging: a case report

Fiore,

Gombert,

La Rosa

et al. 2024

Front. Endocrinol.

View full text Add to dashboard Cite

show abstract

“…In another study, technetium-99m sestamibi single-photon emission CT/CT was also found to be conducive to achieving accurate anatomical localization. 27 …”

Section: Discussionmentioning

confidence: 99%

“…In another study, technetium-99m sestamibi single-photon emission CT/CT was also found to be conducive to achieving accurate anatomical localization. 27 Immunohistochemistry is of major significance to the differential diagnosis among GISTs, leiomyomas, and gastrointestinal autonomic nerve tumors. Schwannomas are positive for S100 protein and vimentin but negative for CD34 and CD117, which is in stark contrast to GISTs.…”

Section: Discussionmentioning

confidence: 99%

Gastric schwannoma: a case report and literature review

Zhang

2020

J Int Med Res

View full text Add to dashboard Cite

Background Gastric schwannoma is a rarely seen gastric tumor accounting for only 0.2% of all gastric tumors. It is difficult to distinguish a gastric schwannoma from other gastric tumors preoperatively. Case presentation: A 30-year-old man with no significant medical history or physical examination findings presented with a 1-month history of right upper abdominal discomfort. The preoperative diagnosis was a gastrointestinal stromal tumor, but the postoperative pathologic and immunohistochemical examinations confirmed a gastric schwannoma. The patient underwent laparoscopic wedge resection of the stomach without additional postoperative treatment, and his postoperative recovery was uneventful. No recurrence or metastasis was found at the 2-year follow-up examination. Conclusion Although gastric schwannomas are usually not malignant, they are difficult to distinguish from other malignant stromal tumors preoperatively. Surgical resection should be recommended when a schwannoma is malignant or considered to be at risk of becoming malignant.

show abstract