A 15-year follow-up study on the outcome in patients with early rheumatoid arthritis

Miyagi, Kenichi; Azuma, Takeshi; Naitoh, Akifumi; Sakaida, Hiroyuki; Sakata, Moromichi; Nakagawa, Takemasa; Miyahara, Hideo; Shirataka, Masuo

doi:10.1007/bf03041335

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2012

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“…A similar approach60 showed a statistically significant longitudinal relationship between joint damage at baseline and HAQ at 9 years (p<0.0001) using a mixed model regression analysis in 115 Dutch patients. Finally, a 74 patient Japanese study54 estimated the factors predicting prognosis by a logistic regression analysis for quality of life score as the endpoint variable, with a statistically significant relationship between initial Steinbrocker's stage and quality of life even after 15 years.…”

Section: Resultsmentioning

confidence: 99%

The relationship between joint damage and functional disability in rheumatoid arthritis: a systematic review

Bombardier

Barbieri²,

Parthan³

et al. 2012

Annals of the Rheumatic Diseases

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While many of the studies did not include multivariate analysis with confounder adjustment, the published evidence indicates a link between joint damage and functional disability and that an increase in joint damage is associated with an increase in disability over time. Treatments to limit progressive joint damage may lead to better joint function and improved patient outcome with less disability.

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Section: Resultsmentioning

confidence: 99%