A 5 year trend and predictors of preterm births in single referral centre of the Greater Kuala Lumpur, Malaysia

Sutan, Rosnah; Mohamed, Nur Ezdiani; Mahdy, Zaleha Abdullah; Ishak, Shareena; Shamsuddin, Khadijah; Idris, Idayu Badilla; Ahmad, Shuhaila; Jaafar, Rosmina; Ismail, Aniza; Sulong, Saperi

doi:10.15406/ipcb.2018.04.00126

Cited by 10 publications

(14 citation statements)

References 21 publications

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“…Similarly, the pooled result shows multiple pregnancies are more likely to be delivered preterm. The result is consistent with other reported studies [ 11 , 58 , 69 – 71 ]. This is due to overstretching of uterus might stimulate early labor.…”

Section: Discussionsupporting

confidence: 94%

Epidemiology of preterm birth in Ethiopia: systematic review and meta-analysis

Muchie

Lakew

Teshome

et al. 2020

BMC Pregnancy Childbirth

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Background Globally, complications of preterm birth are among the most common cause of neonatal mortality. In Ethiopia, the neonatal mortality reduction is not worthy of attention. Hence, this study reviewed the prevalence of preterm birth and factors associated with preterm birth in Ethiopia. Methods The review protocol of this study has been registered in PROSPERO (CRD42017077356). The PRISMA guideline was followed for this review. Studies that assessed the prevalence and/or associated factors of preterm birth in Ethiopia and published from Jan 01, 2009 to Dec 31, 2019 were considered. Studies were searched from the PubMed and Science Direct among medical electronic databases and Google Scholar. Random-effects model was used for detected heterogeneity among studies. Publication bias and sensitivity analysis were assessed. Pooled estimates with its 95% confidence interval were reported using forest plots. The quality of evidence from the review was assessed using GRADE approach. Results Twenty-two studies involving a total of 12,279 participants were included. The overall pooled prevalence of preterm birth in Ethiopia was 10.48% (95% CI: 7.98–12.99). Pooled odds ratio showed rural residence (AOR = 2.34, 95% CI: 1.35–4.05), being anemic (AOR = 2.59, 95% CI: 1.85–3.64), < 4 antenatal care visits (AOR = 2.34, 95%CI: 1.73–3.33), pregnancy induced hypertension (AOR = 3.49, 95% CI: 2.45–4.97), prelabor rapture of membrane (AOR = 4.42, 95% CI: 2.28–8.57), antepartum hemorrhage (AOR = 5.02, 95% CI: 2.90–8.68), multiple pregnancies (AOR = 3.89, 95% CI: 2.52–5.99), past adverse birth outcomes (AOR = 3.24, 95% CI: 2.53–4.15) and chronic illness (AOR = 4.89, 95%CI: 3.12–7.66) were associated with increased likelihood of preterm birth. Further, support during pregnancy was associated with reduced occurrence of preterm birth. Conclusion The pooled national level prevalence of preterm birth in Ethiopia is high. Socio demographic, nutritional, health care, obstetric and gynecologic, chronic illness and medical conditions, behavioral and lifestyle factors are the major associated factors of preterm birth in Ethiopia. This evidence is graded as low grade. Thus, efforts should be intensified to address reported risk factors to relieve the burden of preterm birth in the study setting, Ethiopia.

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Section: Discussionsupporting

confidence: 94%

Epidemiology of preterm birth in Ethiopia: systematic review and meta-analysis

Muchie

Lakew

Teshome

et al. 2020

BMC Pregnancy Childbirth

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“…There is a possibility that cases were not always reported adequately. This is consistent with other studies that used electronic database information ( 75 , 76 ). Our study was conducted at a single tertiary healthcare center; hence the data may not be representative of outcomes in smaller facilities or in other communities outside the research setting, i.e., there is a lack of external validity.…”

Section: Discussionsupporting

confidence: 93%

Prevalence, maternal characteristics, and birth outcomes of preeclampsia: A cross-sectional study in a single tertiary healthcare center in greater Kuala Lumpur Malaysia

Sutan

Aminuddin

Mahdy

2022

Front. Public Health

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BackgroundPreeclampsia is associated with an increased risk of adverse maternal and perinatal outcomes. This study aimed to assess preeclampsia prevalence in a Malaysian referral maternity hospital and the association between preeclampsia and maternal characteristics and outcomes.MethodsA cross-sectional study was conducted between January 2010 and December 2020 using secondary data from a single tertiary healthcare center in Greater Kuala Lumpur, Malaysia. A total of 40,212 deliveries were included for analysis to investigate the association between conditions (maternal characteristics and adverse birth outcomes) and preeclampsia. Multivariable logistic regression was conducted to assess the association between multiple independent variables and the outcome variable (preeclampsia).ResultsThe reported prevalence of preeclampsia was 1.6%. Pregnant women with preeclampsia had a higher risk of preterm delivery (67.7%), instrumental and cesarean delivery (74.7%), neonatal low birth weight (48.5%), neonatal 5-min Apgar score <7 (18.1%), and neonatal intensive care unit (NICU) admission (19.8%). There were significantly higher odds of developing preeclampsia among nullipara [adjusted odd ratio (adjOR) 1.792, 95% CI: 1.518–2.115], women with a previous history of preeclampsia (adjOR 5.345, 95% CI: 2.670–10.698) and women with multiple pregnancies (adjOR 1.658, 95% CI: 1.071–2.566). However, there is a significant association between maternal characteristic variables. There was a significant association when a combination of variables for risk assessment: the presence of anemia and gestational hypertension effect on preeclampsia (OR 26.344, 95% CI: 9.775–70.993, p < 0.002) and gestational hypertension without anemia on preeclampsia (OR 3.084, 95% CI: 2.240–4.245, p < 0.001). Similarly, an association was seen between chronic hypertension and younger age (<35 years old) on preeclampsia (OR 14.490, 95% CI: 9.988–21.021, p < 0.001), and having chronic hypertension with advanced maternal age (≥35 years old) on preeclampsia (OR 5.174, 95% CI: 3.267–8.195, p < 0.001). Both conditions had increased odds of preeclampsia, in varying magnitudes. Overall, the significant interaction effects suggest that a history of chronic or gestational hypertension has a different relationship to the incidence of preeclampsia depending on the maternal age and anemia status. Pregnant women with preeclampsia had significantly higher odds for preterm delivery (adjOR 6.214, 95% CI: 5.244–7.364), instrumental and cesarean delivery (adjOR 4.320, 95% CI: 3.587–5.202), neonatal low birth weight (adjOR 7.873, 95% CI: 6.687–9.271), 5-min Apgar score <7 (adjOR 3.158, 95% CI: 2.130–4.683), and NICU admission (adjOR 8.778, 95% CI: 7.115–10.830).ConclusionsNulliparity, previous history of preeclampsia, and multiple pregnancies were associated with an increased risk of preeclampsia. The presence of different underlying conditions, such as chronic hypertension, anemia, and extremes of maternal age played an important role in increasing preeclampsia risk in the considered study. Larger samples are needed to validate such findings.

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“…Having multiple pregnancy increased the probability of PTB. It is in line with other studies [17,91].This may be due to overstretching of uterus and deciding to complete pregnancy before term. Furthermore, it may be due to spontaneous labor or PROM.…”

Section: Discussionsupporting

confidence: 92%

Determinants of preterm birth among mothers who gave birth in East Africa: systematic review and meta-analysis

Laelago¹,

Yohannes

Tsige

2020

Ital J Pediatr

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Background: Preterm birth (PTB) can be caused by different factors. The factors can be classified into different categories: socio demographic, obstetric, reproductive health, medical, behavioral and nutritional related. The objective of this review was identifying determinants of PTB among mothers who gave birth in East African countries. Methods: We have searched the following electronic bibliographic databases: PubMed, Google scholar, Cochrane library, AJOL (African journal online). Cross sectional, case control and cohort study published in English were included. There was no restriction on publication period. Studies with no abstracts and or full texts, editorials, and qualitative in design were excluded. Funnel plot was used to check publication bias. I-squared statistic was used to check heterogeneity. Pooled analysis was done by using fixed and random effect model. The Joanna Briggs Critical Appraisal Tools for review and meta-analysis was used to check the study quality. Results: A total of 58 studies with 134,801 participants were used to identify determinants of PTB. On pooled analysis, PTB was associated with age < 20 years (AOR 1.76, 95% CI: 1.33-2.32), birth interval less than 24 months (AOR 2.03, 95% CI 1.57-2.62), multiple pregnancy (AOR 3.44,95% CI: 3.02-3.91), < 4 antenatal care (ANC) visits (AOR 5.52, 95%

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A 5 year trend and predictors of preterm births in single referral centre of the Greater Kuala Lumpur, Malaysia

Cited by 10 publications

References 21 publications

Epidemiology of preterm birth in Ethiopia: systematic review and meta-analysis

Epidemiology of preterm birth in Ethiopia: systematic review and meta-analysis

Prevalence, maternal characteristics, and birth outcomes of preeclampsia: A cross-sectional study in a single tertiary healthcare center in greater Kuala Lumpur Malaysia

Determinants of preterm birth among mothers who gave birth in East Africa: systematic review and meta-analysis

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