A 6‐month, randomized, double‐blind, placebo‐controlled study evaluating the ability of a marine complex supplement to promote hair growth in men with thinning hair

Ablon, Glynis

doi:10.1111/jocd.12265

Cited by 34 publications

(51 citation statements)

References 16 publications

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“…More complex blends, such as marine proteins and plant‐derived actives, elicited higher total hair count and density in males with AGA (Norwood scale II and III) , as well as total hair count and the hair diameter of fine hair in healthy females with self‐perceived thinning hair . These studies lasted 6 months, were based on 40–72 participants and included placebo groups.…”

Section: Phytochemicals For Hair Loss Treatmentmentioning

confidence: 99%

Can plant‐derived phytochemicals provide symptom relief for hair loss? A critical review

Daniels

Akram

Westgate

et al. 2019

Intern J of Cosmetic Sci

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It is known that hair growth disorders and hair loss can cause personal distress and affect well‐being. Whilst clinical conditions remain a target for medical research, current research on hair follicle biology and hair growth control mechanisms also provides opportunities for a range of non‐medical and cosmetic interventions that have a modulating effect on the scalp and follicle function. Furthermore, an improvement of the hair fibre characteristics (cuticle structure, cortex size and integrity) could add to the overall positive visual effect of the hair array. Since phytochemicals are a popular choice because of their traditional appeal, this review provides a critical evaluation of the available evidence of their activity for hair benefit, excluding data obtained from animal tests, and offers recommendations on improving study validity and the robustness of data collection in pre‐clinical and clinical studies.

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Section: Phytochemicals For Hair Loss Treatmentmentioning

confidence: 99%

Can plant‐derived phytochemicals provide symptom relief for hair loss? A critical review

Daniels

Akram

Westgate

et al. 2019

Intern J of Cosmetic Sci

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“…Two recent trials by Ablon and colleagues [50,51] reported a significant improvement in hair counts and hair volume with the use of oral marine protein supplement (MPS). Using oral MPS 3 times daily in 100 females with self-perceived hair loss for 6 months demonstrated a significant increase in the mean hair diameter of vellus-like hairs, as well as a reduction in shedding [50].…”

Section: Marine Proteinsmentioning

confidence: 99%

“…Using oral MPS 3 times daily in 100 females with self-perceived hair loss for 6 months demonstrated a significant increase in the mean hair diameter of vellus-like hairs, as well as a reduction in shedding [50]. Sixty males with AGA were treated with oral MPS twice daily for 6 months, resulting in significant increases in total hair count, total hair density, and terminal hair density, as well as fewer hairs extracted on the hair-pull test [51]. MPS appears to be an effective, well-tolerated CAM for patients with hair loss with no adverse events reported.…”

Section: Marine Proteinsmentioning

confidence: 99%

“…Originally marketed as Hairgain ® (Parexel, Norway) and later Viviscal ® (Hair Nourishment System: Lifes2good, Inc., Chicago, IL, USA), marine peptide complexes are thought to enhance the proliferation of dermal papillae cells and increase levels of alkaline phosphatase, an indicator of anagen phase [38]. As summarized in a recent review, eight clinical trials and seven cohort studies demonstrated the ability of proprietary marine proteins, lipids, and glycosaminoglycans to promote growth of terminal and vellus hairs, increase hair shaft diameter, and decrease hair loss [36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51].…”

Section: Marine Proteinsmentioning

confidence: 99%

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Complementary and Alternative Treatments for Alopecia: A Comprehensive Review

Hosking

Juhász

Mesinkovska

2018

Skin Appendage Disord

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The treatment of alopecia is limited by a lack of therapies that induce and sustain disease remission. Given the negative psychosocial impact of hair loss, patients that do not see significant hair restoration with conventional therapies often turn to complementary and alternative medicine (CAM). Although there are a variety of CAM treatment options on the market for alopecia, only a few are backed by multiple randomized controlled trials. Further, these modalities are not regulated by the Food and Drug Administration and there is a lack of standardization of bioactive in gredients in over-the-counter vitamins, herbs, and supplements. In this article, we provide a comprehensive review of the efficacy, safety, and tolerability of CAM, including natural products and mind and body practices, in the treatment of hair loss. Overall, there is a need for additional studies investigating CAM for alopecia with more robust clinical design and standardized, quantitative outcomes.

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“…However, over the past few years, several so-called nutraceuticals for skin and hair conditions have appeared in the market place [4]. Recently, a nutraceutical supplement based on a new marine complex formulation has been developed to promote hair growth (Viviscal® , Life2good, Inc., Chicago, IL, USA) [4,8].…”

Section: Introductionmentioning

confidence: 99%

The Beneficial Effects of an Oriental Herbal Complex Supplement on Women’s Hair and Scalp Conditions: A 24-week, Randomized, Double-blind, Placebo-controlled Study

Kim¹,

Jeon²,

Kim³

et al. 2017

JFNR

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Purpose: Diet is an environmental factor with the potential to significantly influence body changes. Up to now, no study has investigated the effects of the black bean-licorice-biotae folium extract on humans. Therefore, in this study, we examined the effects of this extract on hair and scalp -with regard to total hair number, hair diameter, scalp moisture and sebum. Materials and Method: This study was a randomized, double-blind clinical trial with a 28 week duration. At the -4 week time point of test product intake, participants were enrolled according to criteria and underwent a washout period (4 weeks). At weeks 0, subjects were randomly assigned to one of two treatment regimens: (i) placebo product (4 capsules/day, 700 mg/capsule) or (ii) test product (4 capsules/day, 700 mg/capsule). At weeks 0 and 24, we performed a visual assessment, hair number count and hair diameter, scalp hydration level and sebum excretion level. Results: Expert assessment was positive for the test group. Although the effect on the hair density was not significant, it was positive. Additionally, the hair diameter in the test group significantly increased and significantly decreased in the placebo group. For scalp hydration, the effect was only positive. However, for sebum, the complex appeared to help sebum secretion decrease. There were no safety issues. Conclusion: This study shows that this oriental herbal complex supplement (a Black Bean (Glycine max), Licorice (Glycyrrhiza uralensis Fisch), and Biotae Folium (Thuja orientalis) mixture) is probably effective in improving hair and scalp conditions.

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A 6‐month, randomized, double‐blind, placebo‐controlled study evaluating the ability of a marine complex supplement to promote hair growth in men with thinning hair

Abstract: The results of this study showed for the first time that a dietary supplement containing a marine complex and other ingredients can decrease hair shedding and promote hair growth in men with thinning hair.

Cited by 34 publications

References 16 publications

Can plant‐derived phytochemicals provide symptom relief for hair loss? A critical review

Can plant‐derived phytochemicals provide symptom relief for hair loss? A critical review

Complementary and Alternative Treatments for Alopecia: A Comprehensive Review

The Beneficial Effects of an Oriental Herbal Complex Supplement on Women’s Hair and Scalp Conditions: A 24-week, Randomized, Double-blind, Placebo-controlled Study

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