A Biomedical Perspective in Terahertz Nano-Communications—A Review

Yin, Xiaoxia; Baghai-Wadji, A.R.; Zhang, Yanchun

doi:10.1109/jsen.2022.3161013

Cited by 29 publications

(9 citation statements)

References 118 publications

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“…SNR determines maximum absorption coefficient which is in turn determined by accuracy of signal's amplitude and phase rather than samples. In biomedical applications, reflection mode of THz TDS is commonly preferred over transmission due to water's high absorption of THz radiation which constraints the transmission spectrum of the system [49], [50], [51]. Additional THz imaging and spectroscopy techniques include near-field THz imaging, THz Computed Tomography (CT), THz endoscopy and holography etc.…”

Section: ) Fundamentals Of Thz Pulsed Imagingmentioning

confidence: 99%

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Gezimati

Singh

2023

IEEE Access

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There is a keen interest in the exploration of new generation emitters and detectors due to advancements in innovation of new materials and device processing technologies which have opened up new frontiers in the Terahertz (THz) spectrum. Therefore, it is necessary to review the developments in THz technology for healthcare applications, their impact, implications and prospects for ongoing research and development. This paper provides a broad overview of the current status and prospects of application of THz imaging and sensing for the healthcare domain. We present current knowledge, identify existing challenges for wide scale clinical adoption of THz systems and prospective opinions to facilitate research and development towards optimized and miniaturized THz systems and biosensors that provide real operational convenience through emerging trends. Firstly, we provide an overview of the THz imaging and sensing techniques that exploit properties of THz generation and detection with emphasis on terahertz time domain spectroscopy (THz-TDS) and THz Metamaterials. The mechanisms of tissue image contrast and the application of THz imaging and sensing for biomedical applications in particular, the cancer detection application is reported. Secondly, an outlook toward the advancements in THz technology in the interface of healthcare 4.0 and its enabling technologies is explored for next generation smart and connected healthcare systems. Third, we identify the merits and existing challenges in THz cancer imaging and sensing and suggest prospective opinions to pave way to ongoing and future research. Further, we discuss the recent advances in THz imaging development and the contribution of near-field techniques based on plasmonic, and resonance based metasurfaces, waveguides etc. for breaking the diffraction limit towards development of THz systems that are convenient for point of care. We bring researchers a roadmap for future research scope.

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Section: ) Fundamentals Of Thz Pulsed Imagingmentioning

confidence: 99%

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Gezimati

Singh

2023

IEEE Access

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“…Several ground-based and space-based terahertz astronomical projects have been established internationally, including ALMA, Herschel, and SOFIA. The Terahertz technology not only plays a pivotal role in the domains of astrophysics and cosmology, but also exhibits immense potential in applications, such as security 1 , communications 2 , and chemical drug development 3 .…”

Section: Introductionmentioning

confidence: 99%

Broadband anti-reflection coating with diamond and PTFE for terahertz detectors

Wang,

Zhou,

Fan

et al. 2023

Infrared, Millimeter-Wave, and Terahertz Technologies X

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“…Many organic and biological macromolecules, such as amino acids, lipids, nucleic acids (DNA and RNA), and proteins, have absorption peaks in the terahertz band, and have been studied using terahertz spectroscopy. 4,5 In addition, terahertz waves can reflect weak interactions between molecules (such as hydrogen bond, van der Waals force, etc. ), skeleton vibration and dipole rotation, containing unique information about the composition, structure and function of molecules, which is not achievable in other electromagnetic segments.…”

Section: Introductionmentioning

confidence: 99%

“…In addition to using the terahertz spectroscopy to study DNA, RNA, and protein biomacromolecules, researchers also conduct research studies on microorganisms, such as cancer cells, viruses, bacteria and fungi. For example, according to the specific water content of cells, it is more sensitive to distinguish cancer cells in tissues, [6][7][8] and to distinguish several avian influenza viruses 9,10 and bacteria 4,11 through terahertz characteristic absorption peaks.…”

Section: Introductionmentioning

confidence: 99%