A blood viscosity analyzer

Dobrovol'skii, N. A.; Lopukhin, Yu. M.; Парфенов, А. С.; Peshkov, Anton

doi:10.1007/bf02369060

Cited by 12 publications

(5 citation statements)

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“…Our analysis shows that viscosity of blood without salt added (i.e., 10.07 mPa s) is in excellent agreement with the literature, where a value of ~10 mPa s is reported [34,35]. The slight difference ~0.7% is neg ligible but is discussable to dig out the possible reasons.…”

Section: Signal Processing: Autocorrelationsupporting

confidence: 90%

M-mode swept source optical coherence tomography for quantification of salt concentration in blood: An in vitro study

et al. 2012

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We report the use of M mode swept source optical coherence tomography (SS OCT) for measur ing sodium chloride (NaCl) salt concentrations in liquid phantoms and in drawn whole blood based on tem poral dynamics of light scattering. The Brownian motion of scattering particle is affected due to the change in viscosity of liquid. An autocorrelation function was determined from the power spectrum of SS OCT signal and then was fit by mono and double exponential function to obtain decorrelation time. These translational decorrelation times corresponding to translational diffusion coefficients enabled us to find the controlled vis cosity of the medium. The viscosities of the media were compared with literature values and a fair/excellent agreement was observed. Thus, the technique has ability to quantify the salt levels in terms of viscosity in non flowing medium suspensions and many research routes necessary to determine its potential for in vivo appli cations.

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Section: Signal Processing: Autocorrelationsupporting

confidence: 90%

M-mode swept source optical coherence tomography for quantification of salt concentration in blood: An in vitro study

et al. 2012

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“…Because the blood viscosity at low shear rate is greatly affected by the RBCs' aggregation, the ratio of viscosities at 20 and 100 s −1 can be regarded as quantitative characteristics of the RBC aggregation efficiency (Aggregation index) [32].…”

Section: Rheological Analysismentioning

confidence: 99%

Radio-mitigation effect of poly-MVA after exposure to an acute dose of gamma radiation

El-Marakby

Selim

Desouky

et al. 2016

Journal of Taibah University for Science

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Adult male rats were exposed to a 6 Gy single dose from a Cs-137 source. The radio-mitigation effect of poly-MVA was evaluated by daily administration of 2 ml/kg of body weight immediately after irradiation for two weeks. The morphological changes in the red blood cells were studied. The osmotic fragility and rheological properties of blood, the alteration in the contents of antioxidant enzymes (glutathione, catalase and superoxide dismutase) and lipid peroxidation in hepatic cells were determined. The results showed that exposure to radiation resulted in significant changes in cellular antioxidant enzymes (GSH, catalase and SOD) and a decrease in the blood Bingham viscosity, yield stress and aggregation index. Furthermore, it induced a slight increase in the average osmotic fragility of red blood cells accompanied by a decrease in osmotic dispersion, as well as a modification of red blood cell morphology. It also caused a significant increase (75%) in the lipid peroxidation 1 day after exposure to radiation, which persisted until the 14 th day recorded after irradiation. Oral administration of poly-MVA after irradiation reduced the radiation-induced damage, as seen in the non-significant change in lipid peroxidation compared to the control. It also resulted in improvement in the observed parameters.

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“…For example, people who suffer from heart attacks and strokes have a high level of blood viscosity. [40] From Eq. ( 2), we can see that the dynamics of pore radius have a certain functional relationship with viscosity.…”

Section: Resultsmentioning

confidence: 99%

Regulation of the intermittent release of giant unilamellar vesicles under osmotic pressure

Zhou¹,

Wang²,

Ma³

et al. 2022

Chinese Phys. B

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Osmotic pressure can break the fluid balance between intracellular and extracellular solutions. In hypo-osmotic solution, water molecules, which transfer into the cell and burst, are driven by the concentrations difference of solute across the semi-permeable membrane. The complicated dynamic processes of the intermittent burst have been previously observed. However, the underlying physical mechanism has yet to be thoroughly explored and analyzed. Here, the intermittent release of inclusion in giant unilamellar vesicles was investigated quantitatively, applying the combination of experimental and theoretical methods in the hypo-osmotic medium. Experimentally, we adopted highly sensitive EMCCD to acquire intermittent dynamic images. Notably, the component of the vesicle phospholipids affected the stretch velocity, and the prepared solution of the vesicle adjusted the release time. Theoretically, we chose equations numerical simulations to quantify the dynamic process in phases and explored the influence of physical parameters such as bilayer permeability and solution viscosity on the process. It was concluded that the time taken to achieve the balance of giant unilamellar vesicles was highly dependent on the structure of the lipid molecular. The pore lifetime was strongly related with the internal solution environment of giant unilamellar vesicles. The vesicle prepared in viscous solution accessed visualized long-lived pore. Furthermore, the line tension was measured quantitatively by the release velocity of inclusion, which was in the same order of magnitude as the theoretical simulation. In all, the experimental values well matched the theoretical values. Our investigation clarified the physical regulatory mechanism of intermittent pore formation and inclusion release, which had an important reference for the development of novel technologies such as gene therapy based on transmembrane transport as well as controlled drug delivery based on liposomes.

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A blood viscosity analyzer

Cited by 12 publications

References 0 publications

M-mode swept source optical coherence tomography for quantification of salt concentration in blood: An in vitro study

M-mode swept source optical coherence tomography for quantification of salt concentration in blood: An in vitro study

Radio-mitigation effect of poly-MVA after exposure to an acute dose of gamma radiation

Regulation of the intermittent release of giant unilamellar vesicles under osmotic pressure

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