A Brief Overview on Antioxidant Activity Determination of Silver Nanoparticles

Abstract

Our objective in this review article is to find out relevant information about methods of determination of antioxidant activity of silver nanoparticles. There are many studies dealing with mentioned problem and herein we summarize the knowledge about methods evaluating the antioxidant activity of silver nanoparticles reported so far. Many authors declare better antioxidant activity of silver nanoparticles compared to the extract used for synthesis of them. In this review, we focused on methods of antioxidant activity determination in detail to find out novel and perspective techniques to solve the general problems associated with the determination of antioxidant activity of silver nanoparticles.

Different cellulosic polymers for synthesizing silver nanoparticles with antioxidant and antibacterial activities

“…The antioxidant activity of AgNPs has been studied widely 38 . In addition, it was also investigated for AgNPs prepared via biological, physical, and chemical methods 39 , 40 .…”

All That Glitters Is Not Silver—A New Look at Microbiological and Medical Applications of Silver Nanoparticles

“…Through various synthesis methods, it was possible to create nano forms with spherical, longitudinal or triangular shapes, which also effectively impairs antibacterial activity. It turned out that silver nanoparticles in the shape of trimmed triangular flakes have the strongest bactericidal and antifungal potential in dental implants [ 29 , 30 , 31 ].…”

“…Ionic silver was replaced by nanoparticle form due to its susceptibility to complexing and precipitation. It is also suggested that AgNPs cause fewer side effects, and their safety and antibacterial potential can be further enhanced by various modifications, such as an addition of stabilizers [ 30 , 31 , 32 , 33 ]. It has also been shown that AgNPs have an inhibitory effect on various microorganisms (including Escherichia coli , Salmonella enteritidis , Listeria monocytogenes , Pseudomonas aureginosa , Staphylococcus aureus , Candida albicans ), which was determined in vitro at around 10–15 ppm [ 9 , 30 , 31 , 32 , 33 ].…”

“…It is also suggested that AgNPs cause fewer side effects, and their safety and antibacterial potential can be further enhanced by various modifications, such as an addition of stabilizers [ 30 , 31 , 32 , 33 ]. It has also been shown that AgNPs have an inhibitory effect on various microorganisms (including Escherichia coli , Salmonella enteritidis , Listeria monocytogenes , Pseudomonas aureginosa , Staphylococcus aureus , Candida albicans ), which was determined in vitro at around 10–15 ppm [ 9 , 30 , 31 , 32 , 33 ]. The same AgNPs enriching drinking water for quail and poultry did not inhibit the number of most gastrointestinal bacteria; however, an increase in the number of lactic acid bacteria was observed [ 4 , 24 , 26 , 32 ].…”

“…The metal cations present in the cytoplasm are not effectively removed from the cell as a result of damage caused by NPs. Silver in ionic form reacts with thiol groups of peptides and enzymatic proteins as well as phosphorus-containing bases, disrupting cell metabolism and also causing oxidative stress [ 30 , 58 ].…”