A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension

Olsen, Michael Hecht; Angell, Sonia Y.; Asma, Samira; Boutouyrie, Pierre; Burger, Dylan; Chirinos, Julio A.; Damasceno, Albertino; Delles, Christian; Gimenez-Roqueplo, Anne-Paule; Hering, Dagmara; López‐Jaramillo, Patricio; Martínez, Fernando; Perkovic, Vlado; Rietzschel, Ernst; Schillaci, Giuseppe; Schutte, Aletta E.; Scuteri, Angelo; Sharman, James E.; Wachtell, Kristian; Wang, Tzung‐Dau

doi:10.1016/s0140-6736(16)31134-5

Cited by 778 publications

(605 citation statements)

References 434 publications

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“…A National Heart, Lung, and Blood Institute advisory on Primary Prevention of Hypertension and the Lancet Commission on Hypertension has identified the promotion of a healthy lifestyle in childhood and young adulthood, with a particular focus on lowering caloric intake combined with an increase in physical activity, as critical in the prevention of hypertension 34, 35. The current study supports these recommendations and suggests that primordial prevention beginning at a young age may be effective in preventing hypertension in some young adults, but may not fully eliminate disparities in hypertension incidence by race.…”

Section: Discussionmentioning

confidence: 99%

Cumulative Incidence of Hypertension by 55 Years of Age in Blacks and Whites: The CARDIA Study

Thomas

Booth

Dai

et al. 2018

JAHA

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BackgroundBlacks have higher blood pressure levels compared with whites beginning in childhood. Few data are available on racial differences in the incidence of hypertension from young adulthood through middle age.Methods and ResultsWe calculated the cumulative incidence of hypertension from age 18 to 55 years among participants in the CARDIA (Coronary Artery Risk Development in Young Adults) study. Incident hypertension was defined by the first visit with mean systolic blood pressure ≥130 mm Hg, mean diastolic blood pressure ≥80 mm Hg, or self‐reported use of antihypertensive medication. Among 3890 participants without hypertension at baseline (aged 18–30 years), cumulative incidence of hypertension by age 55 years was 75.5%, 75.7%, 54.5%, and 40.0% in black men, black women, white men, and white women, respectively. Among participants with systolic blood pressure/diastolic blood pressure <110 and 70, 110 to 119/70 to 74, and 120 to 129/75 to 79 mm Hg at baseline, blacks were more likely than whites to develop hypertension: multivariable‐adjusted hazard ratios 1.97 (95% confidence interval, 1.65, 2.35), 1.80 (95% confidence interval, 1.52, 2.14), and 1.59 (95% confidence interval, 1.31, 1.93), respectively. Parental history of hypertension and higher body mass index, serum uric acid, and systolic blood pressure/diastolic blood pressure categories were associated with a higher risk for hypertension among blacks and whites. A higher Dietary Approaches to Stop Hypertension diet adherence score was associated with a lower risk for hypertension in blacks and whites.ConclusionsRegardless of blood pressure level in young adulthood, blacks have a substantially higher risk for hypertension compared with whites through 55 years of age.

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Section: Discussionmentioning

confidence: 99%

Cumulative Incidence of Hypertension by 55 Years of Age in Blacks and Whites: The CARDIA Study

Thomas

Booth

Dai

et al. 2018

JAHA

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“…Elevated blood pressure is a leading cause of cardiovascular disease and related disability worldwide 1. It is a largely preventable condition influenced by a range of lifestyle behaviors, including but not limited to level of physical activity, poor diet, and alcohol consumption.…”

Section: Introductionmentioning

confidence: 99%

“…It is vital that one considers cardiovascular health and its determinants from a life course perspective 1, 7, 8. Raised blood pressure with advancing age is not observed in all societies,9 suggesting that this is not an inevitable part of the aging process.…”

Section: Introductionmentioning

confidence: 99%

Alcohol Consumption, Hypertension, and Cardiovascular Health Across the Life Course: There Is No Such Thing as a One‐Size‐Fits‐All Approach

Bell

2018

JAHA

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“…Hypertension and associated cardiovascular diseases are a global health burden with increasing prevalence across all continents [14–16]. Hypertension is in many cases asymptomatic and awareness of the condition is therefore limited until organ damage, such as stroke, myocardial infarction, or heart failure occur.…”

Section: Introductionmentioning

confidence: 99%

“…Hypertension is in many cases asymptomatic and awareness of the condition is therefore limited until organ damage, such as stroke, myocardial infarction, or heart failure occur. However, even those who are aware of high blood pressure are often not receiving treatment, and blood pressure control rates in treated patients remain low [16,17]. It is evident that in addition to widespread use of existing diagnostic and therapeutic options there must be novel approaches to tackle this global problem.…”

Section: Introductionmentioning

confidence: 99%

Utilizing proteomics to understand and define hypertension: where are we and where do we go?

Delles

Carrick

Graham

et al. 2018

Expert Review of Proteomics

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Introduction: Hypertension is a complex and multifactorial cardiovascular disorder. With different mechanisms contributing to a different extent to an individual’s blood pressure, the discovery of novel pathogenetic principles of hypertension is challenging. However, there is an urgent and unmet clinical need to improve prevention, detection, and therapy of hypertension in order to reduce the global burden associated with hypertension-related cardiovascular diseases.Areas covered: Proteomic techniques have been applied in reductionist experimental models including angiotensin II infusion models in rodents and the spontaneously hypertensive rat in order to unravel mechanisms involved in blood pressure control and end organ damage. In humans proteomic studies mainly focus on prediction and detection of organ damage, particularly of heart failure and renal disease. While there are only few proteomic studies specifically addressing human primary hypertension, there are more data available in hypertensive disorders in pregnancy, such as preeclampsia. We will review these studies and discuss implications of proteomics on precision medicine approaches.Expert commentary: Despite the potential of proteomic studies in hypertension there has been moderate progress in this area of research. Standardized large-scale studies are required in order to make best use of the potential that proteomics offers in hypertension and other cardiovascular diseases.

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A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension

Cited by 778 publications

References 434 publications

Cumulative Incidence of Hypertension by 55 Years of Age in Blacks and Whites: The CARDIA Study

Cumulative Incidence of Hypertension by 55 Years of Age in Blacks and Whites: The CARDIA Study

Alcohol Consumption, Hypertension, and Cardiovascular Health Across the Life Course: There Is No Such Thing as a One‐Size‐Fits‐All Approach

Utilizing proteomics to understand and define hypertension: where are we and where do we go?

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