1998
DOI: 10.1016/s0378-5173(97)00383-9
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A calorimetric study on the idebenone–phospholipid membrane interaction

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Cited by 22 publications
(15 citation statements)
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“…Baselines in the form of constants were subtracted from the curves. The enthalpy value obtained for pure DPPC liposomes was in the range of those described in the literature (18,19), but the presence of peptides in the media decreases the enthalpy associated to the main transition as can be appreciated in the figures of the table. Broadening and depression of the main transition have also been observed for biological peptides (20) interacting with multilamellar lipid bilayers.…”
Section: Differential Scanning Calorimetrymentioning
confidence: 68%
“…Baselines in the form of constants were subtracted from the curves. The enthalpy value obtained for pure DPPC liposomes was in the range of those described in the literature (18,19), but the presence of peptides in the media decreases the enthalpy associated to the main transition as can be appreciated in the figures of the table. Broadening and depression of the main transition have also been observed for biological peptides (20) interacting with multilamellar lipid bilayers.…”
Section: Differential Scanning Calorimetrymentioning
confidence: 68%
“…Thus, any alterations in these properties are indicative of the perturbation of the membrane structure and/or fluidity due to the interaction of the lipid with exogenous molecules in the bilayer. Reports have appeared in literature on drug-model membrane interactions describing how drugs modify the phase transition, fluidity and mobility of the membranes depending on its chemico-physical behaviour and concentration [18][19][20][21][22][23][24][25].…”
Section: Introductionmentioning
confidence: 99%
“…In both model and biomembranes the lipid acyl chain melting (CM) transitions are brought about by acyl chain disordering, which affects their physical attributes relevant to physiological function. The chain melting transition and the associated changes in membrane properties are strongly dependent on factors such as the acyl chain length, the nature of the lipid headgroup, and the presence of small molecules [13][14][15][16][17][18][19][20].…”
Section: Introductionmentioning
confidence: 99%