A case control study of vitamin D levels in patients with vitiligo

Abstract

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Vitiligo is fairly commonly encountered disorder of pigmentation resulting in the presence of numerous depigmented macules and patches over the body. Vitamin D is an essential hormone synthesized in the skin. Levels of vitamin D have been found to be low in patients with vitiligo. The purpose of this study is to evaluate if vitamin D levels have any association with vitiligo, by estimating the levels of vitamin D in patients with vitiligo, and correlating type of vitiligo with vitamin D levels.</span></p><p class="abstract"><strong>Methods:</strong> A hospital based case control study was done in the Dermatology outpatient department of a tertiary center in South India from October 2014 to May 2016. About 45 consenting patients who fulfilled the inclusion criteria were chosen for the study. About 45 age and sex matched consenting individuals without vitiligo were chosen as controls from the Dermatology outpatient department. A detailed history and clinical examination of all the consenting subjects was done. Blood samples were collected from both the cases and controls by venepuncture and sera separated. The levels of Vitamin D were estimated using a vitamin D ELISA kit.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">There was no statistically significant difference in vitamin D levels between patients and controls. There was no correlation between type of vitiligo and vitamin D value. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Vitamin D does not appear to have any role in vitiligo patients in this study.</span></p>

Synthesis, Characterization, and Catalytic Activity of New Cu(II) Complexes of Schiff Base: Effective Catalysts for Decolorization of Acid Red 37 Dye Solution

“…Schiff base metal complexes have been studied extensively because of their attractive chemical and physical properties and their wide range of applications in numerous scientific areas. These types of complexes have been vigorously explored in recent years, and such studies have been the subject of many papers and reviews [13][14][15][16]. The major applications of the Schiff base complexes are in catalysis.…”

Decreased circulatory levels of Vitamin D in Vitiligo: a meta-analysis

“…The available studies in the literature are inconsistent on Vit-D levels and Hypovitaminosis D is still controversial in vitiligo. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 In this updated systematic review and meta-analysis on vitiligo and Vit-D levels (ViViD Study), the serum Vit-D levels and their association with variables like age, disease duration, affected Body Surface Area (BSA), and Vitiligo Activity and Severity Index (VASI) were studied in vitiligo patients as compared to controls. A subgroup meta-analysis was conducted to study Vit-D levels in relation to gender, skin type, Vitiligo type, disease activity, vitiligo history, autoimmune comorbidities, and indoor-outdoor job status of vitiligo patients.…”

Zn(II), Mn(III), and Co(III) complexes of Schiff base derived from 2‐hydroxy‐1‐naphthaldehyde: Synthesis, spectral surveys, single crystal structure studies, Hirshfeld surface analysis, density functional theory calculation, molecular electrostatic potential, and molecular docking evaluations

“…The bands that appeared in the around 403 and 418 nm (1, 2) , 396 and 429 nm (3) , and 438 nm (4) are associated with the CT (charge transfer). For complexes (3, 4) in the 484 and 675 nm districts, d → d transfers were observed, respectively 18,39,40,68–70 …”