A Case-Control Study of Risk Factors for Development of Type 2 Diabetes: Emphasis on Physical Activity.

Wang, Luping; Yamaguchi, Takuhiro; Yoshimine, Toshiko; Katagiri, Akane; Shirogane, Kazuko; Ohashi, Yasuo

doi:10.2188/jea.12.424

Cited by 13 publications

(6 citation statements)

References 25 publications

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“…Physical activity has been associated to a reduced risk for excessive weight gain, insulin resistance and type 2 diabetes mellitus 65,66,67 . Few studies evaluated the association between physical activity and gestational diabetes mellitus, however it has been stated that increasing physical activity could decrease the glucose intolerance in diabetic pregnant women 68 .…”

Section: Physical Activitymentioning

confidence: 99%

Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature

Dode

Santos

2009

Cad. Saúde Pública

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Section: Physical Activitymentioning

confidence: 99%

Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature

Dode

Santos

2009

Cad. Saúde Pública

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“…Wang et al (11) concluded that there is a relationship between physical activity (PA) and reduced risk of type 2 diabetes mellitus. Therefore, inactivity, especially watching television for long durations, increases the risk of diabetes (12).…”

Section: Introductionmentioning

confidence: 99%

The Association Between Physical Activity During Pregnancy and Gestational Diabetes Mellitus: A Case-Control Study

Nasiri-Amiri

Bakhtiari

Faramarzi

et al. 2016

Int J Endocrinol Metab

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BackgroundGestational diabetes mellitus is one of the most common complications of pregnancy. Physical activity is associated with a lower risk of type 2 diabetes mellitus. A recent meta-analysis study suggested that more research is needed to investigate the type, duration and intensity of physical activity that can help to reduce the risk of gestational diabetes mellitus.ObjectivesThe present study aimed to understand the association between physical activity and gestational diabetes mellitus through comparing the type and intensity of physical activity performed by pregnant females with gestational diabetes and healthy pregnant females in the first 20 weeks of their pregnancy.Patients and MethodsIn the current case-control study, 100 pregnant females with gestational diabetes mellitus as the case group and 100 pregnant females as the non-diabetic control group were recruited. The age range of the participants was 18 - 40 years with the gestation of 20 - 28 weeks. To diagnose gestational diabetes mellitus using the criteria introduced by carpenter and coustan females with abnormal glucose challenge test (> 140 mg/dL) were asked to perform the three-hour 100 g oral glucose tolerance test. The details of physical activity were collected by a modified version of the pregnancy physical activity questionnaire. Anthropometric and relevant data were recorded for all of the participants. Data were analyzed by SPSS version 21. Risk estimates were obtained by logistic regression and adjusted for confounders.ResultsFemales who had low total physical activity according to the pregnancy physical activity questionnaire during early pregnancy were at a significantly higher risk of developing gestational diabetes mellitus (OR = 4.12, 95% CI (2.28 - 7.43), P = 0.001) compared to the ones who reported higher levels of physical activity. Moreover, after adjusting for age, body mass index (BMI), gravidity and a family history of diabetes, females with low physical activity in the domain of transportation activity during 20 weeks of pregnancy were at a significantly higher risk of developing gestational diabetes mellitus. The statistical findings indicate that females with the low intensity of sedentary, light and moderate physical activity are at a higher risk of developing gestational diabetes mellitus (OR 2.32; 95% CI 1.21-4.43, P = 0.010, OR 6.26; 95% CI 2.95 - 13.30, P = 0.001 and OR 6.73; 95% CI 3.15 - 14.38, P = 0.001) compared to females with a higher intensity of sedentary, light and moderate physical activity.ConclusionsThe amount and intensity of physical activity during pregnancy is associated with a lower risk of gestational diabetes mellitus. As a result, the pregnant Iranian females have to be encouraged to do regular daily physical activity during pregnancy, if there is no specific contraindication to it.

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“…Another risk factor of diabetes is the lack of physical activity. Previous studies have shown that high levels of physical activity are associated with reduced risk of diabetes [60][61][62][63]. However, about 46% of primary care patients at risk for diabetes did not do physical activity per week [40]; while two-third of patients with diabetes remain inactive [64].…”

Section: Discussionmentioning

confidence: 99%

Principal Component Regression Analysis of Nutrition Factors and Physical Activities with Diabetes

Wang¹,

Liu²,

Xie³

et al. 2017

J Biom Biostat

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The associations of nutrition factors and physical activities with adult diabetes are inconsistent; while most of these factors are inter correlated. The aims of this study are to overcome the disturbance of the multicollinearity of the risk factors and examine the associations of these factors with diabetes using the principal component analysis (PCA) and regression analysis with principal component scores (PCS). Totally, 659 adults with diabetes and 2827 non-diabetic were selected from the 2012 Health Information National Trends Survey (HINTS 4, Cycle 2). PCA was utilized to deal with multicollinearity of the risk factors. Weighted univariate and multiple logistic regression analyses were used to estimate the associations of potential factors and PCS with diabetes. The odds ratios (ORs) with 95% confidence intervals (CIs) were estimated. The first 3 PCs for nutrition factors and physical activities could explain 70% variances. The first principal component (PC 1 ) is a measure of nutrition factors (fruit and vegetables consumption), PC 2 is a measure for physical activities (moderate exercise and strength training), and PC3 is about calorie information use and soda use. Weighted multiple logistic regression showed that African Americans, middle aged adults (45-64 years), elderly (65+), never married, and with lower education were associated with increased odds of diabetes. After adjusting for others factors, the PC 1 showed marginal association with diabetes (OR=0.84, 95% CI=0.70-1.01); while PC 2 and PC 3 revealed significant associations with diabetes (OR=0.73, 95% CI=0.61-0.86 and OR=0.85, 95% CI=0.74-0.99, respectively). In conclusion, PCA can be used to reduce the indicators in complex survey data. The first 3 PCs of nutrition factors and physical activities were associated with diabetes. Promotion of health food and physical activities should be encouraged to help decrease the prevalence of diabetes.

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A Case-Control Study of Risk Factors for Development of Type 2 Diabetes: Emphasis on Physical Activity.

Cited by 13 publications

References 25 publications

Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature

Non classical risk factors for gestational diabetes mellitus: a systematic review of the literature

The Association Between Physical Activity During Pregnancy and Gestational Diabetes Mellitus: A Case-Control Study

Principal Component Regression Analysis of Nutrition Factors and Physical Activities with Diabetes

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