A Case of Angiolymphoid Hyperplasia With Eosinophilia Treated With Intralesional Interferon Alfa-2a

Shenefelt, Philip D.; Rinker, Margaret; Caradonna, Stephanie

doi:10.1001/archderm.136.7.837

Cited by 35 publications

(22 citation statements)

References 19 publications

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“…Recently, the use of intralesional IFN-·2a has been reported [9]. In our patient, we have successfully used intralesional IFN-·2b with the same results.…”

supporting

confidence: 72%

Angiolymphoid Hyperplasia with Eosinophilia: Successful Treatment with Interferon Alpha 2b

et al. 2001

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“…Recently, the use of intralesional IFN-·2a has been reported [9]. In our patient, we have successfully used intralesional IFN-·2b with the same results.…”

supporting

confidence: 72%

Angiolymphoid Hyperplasia with Eosinophilia: Successful Treatment with Interferon Alpha 2b

et al. 2001

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“…Although the etiopathogenesis of ALHE is not fully known, it is mainly related to trauma, hyperestrogenemia, infectious agents, environmental factors (insect bite), atopy, disorders in the immunological mechanism [2,3]. In the literature, it has been reported cases associated with hyper estrogenemic conditions (pregnancy, use of oral contraceptives) [4][5][6][7].…”

Section: Discussionmentioning

confidence: 99%

“…Another option is to follow up the lesion 3-6 months for the possibility of spontaneous regression [2]. Surgical excision which has a high success rate is widely used [10,11].…”

Section: Discussionmentioning

confidence: 99%

“…Although the lesions are usually asymptomatic, they may rarely accompany pain, itching and spontaneous bleeding when pressed on. The etiopathogenesis of ALHE is related to environmental, hormonal and immunological factors [2]. Here, the purpose of our study is to review the literature and to present this vasculo-proliferative disease by reporting two case of ALHE, one pregnant woman and one man.…”

Section: Introductionmentioning

confidence: 99%

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Angiolymphoid Hyperplasia with Eosinophilia: A Study of Two Cases

Sd¹

2017

CDOAJ

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Objective: Angiolymphoid hyperplasia with eosinophilia (ALHE), is presented by multiple pink or red papules and nodules on the head, neck, preauricular area and anterior hairline. Although the lesions are usually asymptomatic, they may rarely accompany pain, pulsation, itching and spontaneous bleeding when is pressed on. The etiopathogenesis of ALHE is related to environmental, allergic, hormonal and immunological factors. Here, the purpose of our study is to review the literature and to observe this vasculo-proliferative disease by reporting two case of ALHE associated with an allergic response, one pregnant one man.Case Report: High serum IgE levels and eosinophilia-rich infiltration on histopathological examination were showed in both of our cases. Additionally, IgE antibody was positive in immunohistochemical examination. These findings support the fact that ALHE lesions may be associated with an allergic response in both of our cases. Conclusion:ALHE, which has a lot of questions in its etiopathogenesis, this disease will be better understood by largescale studies in a large number of studies, so that the appropriate treatment method will be chosen and the recurrences after treatment will be less

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“…Other therapeutic options less commonly used include isotretinoin, interferon, pentoxifylline, imiquimod, cryotherapy and laser. [33][34][35][36][37][38][39][40] …”

Section: Angiolymphoid Hyperplasia With Eosinophilia (Alhe)mentioning

confidence: 99%

Doença de Kimura não é hiperplasia angiolinfóide com eosinofilia: correlação clinicopatológica com revisão da literatura e definição de critérios diagnósticos

Briggs

2006

An. Bras. Dermatol.

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Kimura disease is a rare chronic inflammatory disease that presents as a tumor-like swelling in the head and neck region and is often associated with regional cervical lymphadenopathy. Cases have been described predominantly in the oriental literature. Kimura disease has been confused with angiolymphoid hyperplasia with eosinophilia, for having common characteristics, but both conditions should be differentiated. In this article, the clinical and histopathological characteristics are revised and the criteria to differentiate the two conditions are presented. Keywords: Angiolymphoid hyperplasia with eosinophilia; Hemangioma; Histology Resumo: A doença de Kimura é doença inflamatória crônica que se manifesta como crescimento tumoral indolor na região da cabeça e do pescoço, freqüentemente associada à linfoadenopatia cervical. Por ser doença rara, ter sido descrita inicialmente na literatura oriental e ter características em comum com a hiperplasia angiolinfóide com eosinofilia, a doença de

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A Case of Angiolymphoid Hyperplasia With Eosinophilia Treated With Intralesional Interferon Alfa-2a

Cited by 35 publications

References 19 publications

Angiolymphoid Hyperplasia with Eosinophilia: Successful Treatment with Interferon Alpha 2b

Angiolymphoid Hyperplasia with Eosinophilia: Successful Treatment with Interferon Alpha 2b

Angiolymphoid Hyperplasia with Eosinophilia: A Study of Two Cases

Doença de Kimura não é hiperplasia angiolinfóide com eosinofilia: correlação clinicopatológica com revisão da literatura e definição de critérios diagnósticos

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