A Case of Atypical Thyroid Storm with Hypoglycemia and Lactic Acidosis

Izumi, Kenichi; Kondo, Shin‐ichiro; Okada, Takanori

doi:10.1507/endocrj.k09e-043

Cited by 18 publications

(19 citation statements)

References 8 publications

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“…In a state of hyperthyroidism, facilitated glucose utilization in the presence of hyperinsulinemia is not appropriately counter-regulated 114-116. Hypoglycemia is one of the key features of adrenal insufficiency.…”

Section: Metabolism/ Endocrinologymentioning

confidence: 99%

Hypoglycemia Revisited in the Acute Care Setting

et al. 2011

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Hypoglycemia is a common finding in both daily clinical practice and acute care settings. The causes of severe hypoglycemia (SH) are multi-factorial and the major etiologies are iatrogenic, infectious diseases with sepsis and tumor or autoimmune diseases. With the advent of aggressive lowering of HbA1c values to achieve optimal glycemic control, patients are at increased risk of hypoglycemic episodes. Iatrogenic hypoglycemia can cause recurrent morbidity, sometime irreversible neurologic complications and even death, and further preclude maintenance of euglycemia over a lifetime of diabetes. Recent studies have shown that hypoglycemia is associated with adverse outcomes in many acute illnesses. In addition, hypoglycemia is associated with increased mortality among elderly and non-diabetic hospitalized patients. Clinicians should have high clinical suspicion of subtle symptoms of hypoglycemia and provide prompt treatment. Clinicians should know that hypoglycemia is associated with considerable adverse outcomes in many acute critical illnesses. In order to reduce hypoglycemia-associated morbidity and mortality, timely health education programs and close monitoring should be applied to those diabetic patients presenting to the Emergency Department with SH. ED disposition strategies should be further validated and justified to achieve balance between the benefits of euglycemia and the risks of SH. We discuss relevant issues regarding hypoglycemia in emergency and critical care settings.

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Section: Metabolism/ Endocrinologymentioning

confidence: 99%

Hypoglycemia Revisited in the Acute Care Setting

et al. 2011

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“…Because hypoglycemia was detected at the time of cardiac arrest, hypoglycemia was also regarded as a potential cause. Although hypoglycemia with thyroid crisis has rarely been reported [7,8], adrenal dysfunction is thought to be a potential underlying mechanism in such cases. In our case, the patient's adrenal hormone levels were high.…”

Section: Discussionmentioning

confidence: 99%

Cardiac arrest caused by landiolol in a patient in thyroid crisis

Misumi

Kodera

Nagura

et al. 2016

Journal of Cardiology Cases

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“…Multiple aspects of patient A's presentation of thyroid storm are rare manifestations. Hypoglycaemia and lactic acidosis have only been reported in three other cases 2 3 7. The other rare features are normothermia2 7 and unusually severe multiorgan dysfunction 3 7…”

Section: Discussionmentioning

confidence: 99%

Surviving the storm: two cases of thyroid storm successfully treated with plasmapheresis

et al. 2012

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Thyroid storm is a rare, but critical, illness that can lead to multiorgan failure and carries a high death rate. The following case series describes two adult men with Graves’ disease who presented in thyroid storm and either failed or could not tolerate conventional medical management. However, both patients responded well to plasmapheresis, which resulted in clinical and biochemical stabilisation of their disease processes. The treatment option of plasmapheresis should be considered as a stabilising measure, especially when patients have failed or cannot tolerate conventional therapy. Plasmapheresis leads to amelioration of symptoms and a significant decline in thyroid hormone levels, providing a window to treat definitively with thyroidectomy.

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A Case of Atypical Thyroid Storm with Hypoglycemia and Lactic Acidosis

Cited by 18 publications

References 8 publications

Hypoglycemia Revisited in the Acute Care Setting

Hypoglycemia Revisited in the Acute Care Setting

Cardiac arrest caused by landiolol in a patient in thyroid crisis

Surviving the storm: two cases of thyroid storm successfully treated with plasmapheresis

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