A Case of Choriocarcinoma with Lung Metastasis as the First Symptom

Abstract

Background: Pure testicular choriocarcinoma is very rare in clinic and the patient's age is 20-39 years (median age 29 years). Because of its polymorphic manifestations, it is not always suspected and patients are sometimes misdiagnosed. The case should be reported due to the rarity of the disease ,the onset age and the rapid progression of the disease. This case with primary lung cancer as the first diagnosis is a misdiagnosis. We hope we can provide some experience for clinical diagnosis and treatment. Case presentation: We report the case of a 46-year-old man who was admitted to our hospital with bloodshot sputum. Histopathological and immunohistochemical examination revealed pure choriocarcinoma. The patient had received radiotherapy, chemotherapy, immunotherapy, Over the next 5 months, the patient developed symptoms of multiple system metastases and died soon. Conclusions: Testicular choriocarcinoma is progressing rapidly. The clinical feature of choriocarcinoma is hemorrhaging at the metastatic site. Early diagnosis and timely treatment should be combined with the clinical manifestations and medical history of patients to strive for a longer survival time. We hope this case can provide guidance for the clinical diagnosis and treatment of the disease.