A case of generalized Sweet syndrome with vasculitis triggered by recent COVID-19 vaccination

Kinariwalla, Neha; London, Ashley O; Soliman, Yssra; Niedt, George W.; Husain, Sameera; Gallitano, Stephanie M.

doi:10.1016/j.jdcr.2021.11.010

Cited by 6 publications

(8 citation statements)

References 9 publications

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“…The skin and mucous membranes involvement not typical for classical SS was also reported: pitting edema, nodular erythema of the feet and oral ulcerations 32 . What is more, Janssen vaccination has been linked to generalized SS with vasculitis and transient IgA monoclonal gammopathy 45 . Other types of reported acute febrile neutrophilic dermatosis comprise cellulitis‐like SS and bullous SS 39,43 .…”

Section: Discussionmentioning

confidence: 99%

“… 32 What is more, Janssen vaccination has been linked to generalized SS with vasculitis and transient IgA monoclonal gammopathy. 45 Other types of reported acute febrile neutrophilic dermatosis comprise cellulitis‐like SS and bullous SS. 39 , 43 In the latest publication concerning acute skin reaction after Pfizer‐BioNTech vaccine included in this review, the authors settle the diagnosis of neutrophilic dermatosis with necrobiotic changes.…”

Section: Discussionmentioning

confidence: 99%

“…It was accompanied by vasculitis and transient IgA monoclonal gammopathy and occurred 9 days after the administration. 45 Of note, both vaccination and SARS-CoV-2 infection may provoke SS. 47 The pathogenesis of neutrophilic diseases still is still not fully understood.…”

Section: Discussionmentioning

confidence: 99%

“…Apart from the case presented in the article, there is only one description of SS, triggered by Janssen Ad26.COV2.S vaccine. It was accompanied by vasculitis and transient IgA monoclonal gammopathy and occurred 9 days after the administration 45 . Of note, both vaccination and SARS‐CoV‐2 infection may provoke SS 47 …”

Section: Discussionmentioning

confidence: 99%

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Atypical presentation of Sweet syndrome with nodular erythema and oral ulcerations provoked by Ad26.COV2.SSARS‐CoV‐2 vaccination and review of literature

Bechtold

Owczarczyk‐Saczonek

2022

Dermatologic Therapy

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The aim of this article is to present the case of acute febrile neutrophilic dermatosis (Sweet syndrome-SS) after Ad26.COV2.S vaccination against SARS-CoV-2. To the best of our knowledge, this is the second case of SS provoked by this specific vaccine. What is more, the mildly symptomatic beginning of the disease, later followed by typical SS manifestation with a variety of symptoms including nodular erythema of the feet and oral ulcerations, made it very challenging to establish the diagnosis.The article focuses on the current literature on the acute febrile neutrophilic dermatosis, along with the coexistence with other neutrophilic dermatoses and anti-SARS-CoV-2 vaccinations as provoking factors. It emphasizes the necessity for sharing the knowledge and experience on the subject of SS's clinical manifestations and underlying causes to facilitate prompt diagnosis and introduction of appropriate treatment.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Atypical presentation of Sweet syndrome with nodular erythema and oral ulcerations provoked by Ad26.COV2.SSARS‐CoV‐2 vaccination and review of literature

Bechtold

Owczarczyk‐Saczonek

2022

Dermatologic Therapy

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“…Without association with autoimmune diseases, there were some reports of COVID-19 vaccination-triggered ND, such as pyoderma gangrenosum 12 and Sweet disease, 13…”

Section: Discussionmentioning

confidence: 99%

Autoimmunity‐related neutrophilic dermatosis after coronavirus disease 2019 vaccination: A case report and literature review

Kishibe

Koike²,

Kanno

et al. 2023

The Journal of Dermatology

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Autoimmune diseases triggered by coronavirus disease 2019 (COVID‐19) mRNA vaccination have been emerging. Here, we report the case of a 27‐year‐old Japanese man with autoimmunity‐related neutrophilic dermatosis, occurring as an initial cutaneous manifestation of systemic lupus erythematosus with Sjögren syndrome after the second dose of the Pfizer/BioNTech COVID‐19 vaccination. The patient presented with urticarial erythema and partially annular erythema on the trunk and extremities with severe pruritus. Histopathological analysis showed vacuolar degeneration at the dermo‐epidermal junction and interstitial neutrophil infiltration. We reviewed eight patients, including the aforementioned patient, with exacerbation or new‐onset of SLE after COVID‐19 vaccination and found the patient had relatively mild symptoms, itchy annular erythema, and positive anti‐SS‐A/SS‐B antibodies. COVID‐19 mRNA vaccination can induce the production of type‐I interferon, which plays a crucial role in the pathogenesis of SLE and may cause autoimmunity‐related neutrophilic dermatosis in susceptible individuals. In the case that itchy annular erythema develops approximately 2 weeks after the vaccination, the possibility of systemic or cutaneous lupus erythematosus should be considered. For an accurate diagnosis, dermatologists should obtain a recent vaccination history and perform complete antibody profiling and skin biopsy for patients presenting with annular or erythema multiforme‐like lesions.

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Ad26.cov2-s

2022

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A case of generalized Sweet syndrome with vasculitis triggered by recent COVID-19 vaccination

Cited by 6 publications

References 9 publications

Atypical presentation of Sweet syndrome with nodular erythema and oral ulcerations provoked by Ad26.COV2.SSARS‐CoV‐2 vaccination and review of literature

Atypical presentation of Sweet syndrome with nodular erythema and oral ulcerations provoked by Ad26.COV2.SSARS‐CoV‐2 vaccination and review of literature

Autoimmunity‐related neutrophilic dermatosis after coronavirus disease 2019 vaccination: A case report and literature review

Ad26.cov2-s

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