A case of intoxication relapse of pilsicainide after the transient recovery using hemoperfusion from the toxicity with electrocardiogram (ECG) abnormalities

A case of cardiopulmonary arrest on arrival due to pilsicainide intoxication

“…There are no antidotes or antagonists for pilsicainide, and its removal rate is reported to be as low as 37% on HD, 25% on hemofiltration dialysis, and 45% on plasma exchange. Because a slight decrease in the serum concentration of pilsicainide has been reported to improve symptoms 6) and repeated polymorphic VT occurred in our case, we intervened with HD to try to immediately decrease the serum concentration. Magnesium sulfate was reported 7) as another treatment option.…”