A case of osteitis due to Staphylococcus aureus and Arcanobacterium bernardiae coinfection

Bémer, Pascale; Eveillard, Marion; Touchais, S.; Redon, H; Corvec, Stéphane

doi:10.1016/j.diagmicrobio.2008.10.016

Cited by 18 publications

(15 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…bernardiae has been described as a pathogen in urinary tract infections (Ieven et al, 1996;Lepargnear et al, 1998), joint infections (Adderson et al, 1998;Bemer et al, 2009;Lo ez et al, 2009), skin and soft-tissue infections (Weitzel et al, 2011;Otto et al, 2013), necrotizing fasciitis (Clarke et al, 2010) and a case of eye infection (Funke et al, 1995). Six strains of T. bernardiae have been cultured from blood specimens, but no deaths due to T. bernardiae have been reported.…”

Section: Introductionmentioning

confidence: 99%

A case of diabetic foot ulcers complicated by severe infection and sepsis with Trueperella bernardiae

et al. 2015

View full text Add to dashboard Cite

Introduction: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) allows us to identify bacteria directly from positive blood cultures with detailed taxonomy naming of the bacterial strains. Knowing the name of the infective bacteria makes it possible to adjust the antibiotic therapy early on. However, it also gives rise to detection of a number of unusual pathogens, which raises new questions on the pathogenicity and medical importance of a number of rarely isolated bacteria such as Trueperella bernardiae.Case presentation: We describe a case of diabetic foot ulcers in a 45-year-old male, which led to below-the-knee amputation due to widespread infection and sepsis with T. bernardiae and coinfection with Peptoniphilus lacrimalis. The patient was treated initially with surgical debridement in combination with piperacillin/tazobactam and thereafter with amoxicillin for a total period of 1 month.Conclusion: Based on this case, as well as previous case reports in the literature, we conclude that T. bernardiae is a rarely isolated low-pathogenic bacterium in patients with severe comorbidities. Often co-infection with other low-pathogenic bacteria is observed. T. bernardiae is susceptible to and readily treated with b-lactam antibiotics.

show abstract

Section: Introductionmentioning

confidence: 99%

A case of diabetic foot ulcers complicated by severe infection and sepsis with Trueperella bernardiae

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Given the paucity of susceptibility data, minimum inhibitory concentration interpretive criteria for the genus Corynebacterium can be extrapolated to Arcanobacterium ( Trueperella ) species for interpretation [ 22 ]. Effective treatment of osteoarticular infections caused by Trueperella species has consisted of fluoroquinolones [ 20 , 23 ] and clindamycin [ 9 , 21 ] for durations of 2 to 12 weeks. Our patient was successfully treated with a two-week course of doxycycline which, to our knowledge, has also not been reported in the medical literature.…”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Olecranon Bursitis Caused byTrueperella bernardiae: Importance of Environmental Exposure and Pathogen Identification

Gowe

Parsons

Best

et al. 2018

Case Reports in Infectious Diseases

View full text Add to dashboard Cite

A livestock farmer with a history of arthropathy presented with unilateral olecranon bursal swelling and tenderness. Multiple wound and intraoperative cultures revealed growth of Trueperella bernardiae, a Gram-positive coccobacillus, with symptom resolution following appropriate antimicrobial therapy. To our knowledge, this is the first case report of olecranon bursitis caused by this organism. Coryneform bacteria are often regarded as contaminants in clinical cultures, but advanced techniques for species identification may reveal expanded pathogenic potential of individual species like T. bernardiae and elucidate epidemiologic clues for osteoarticular infections in these cases.

show abstract

“…Les infections documentées à T. bernardiae sont rares. T. bernardiae a été isolé d'abcès cutanéo-muqueux, de septicémies, d'arthrites, d'ostéites, d'un abcès périnéphrétique compliqué d'un pyothorax, d'infections urinaires parfois sévères chez des patients porteurs d'une dérivation urétéro-iléale [31][32][33][34]. Son véritable rôle pathogène est encore mal connu.…”

Section: Trueperella Bernardiae : Futur Uropathogène éMergent ?unclassified

“…Les macrolides ont une excellente activité et sont une alternative au traitement par les bêtalactamines dans des infections autres qu'urinaires. Les traitements des différents cas d'infections humaines à T. bernardiae ont été menés avec succès par bêtalactamines (amoxicilline), clindamycine et acide fusidique, ainsi qu'une association de rifampicine et d'ofloxacine [32][33][34].…”

Section: Trueperella Bernardiae : Futur Uropathogène éMergent ?unclassified

Mise au point : les uropathogènes émergents

Brun¹,

Robert²,

Bruyère³

et al. 2015

Progrès en Urologie

View full text Add to dashboard Cite

A case of osteitis due to Staphylococcus aureus and Arcanobacterium bernardiae coinfection

Cited by 18 publications

References 6 publications

A case of diabetic foot ulcers complicated by severe infection and sepsis with Trueperella bernardiae

A case of diabetic foot ulcers complicated by severe infection and sepsis with Trueperella bernardiae

Successful Treatment of Olecranon Bursitis Caused byTrueperella bernardiae: Importance of Environmental Exposure and Pathogen Identification

Mise au point : les uropathogènes émergents

Contact Info

Product

Resources

About