A Case of Primary Central Nervous System Lymphoma with Ciliary Body Involvement

Li, Meng-Da; Zhao, Chan; Ye, Junjie; Xu, Haiyan

doi:10.4103/0366-6999.181960

Cited by 2 publications

(3 citation statements)

References 4 publications

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“…The identification of lymphoma cells is considered the gold standard for the diagnosis of lymphomatous involvement of ciliary ( 5 ). Pei et al.…”

Section: Discussionmentioning

confidence: 99%

“…The majority of uveal lymphomas are confined to the choroid, while reports of ciliary body involvement have rarely been documented. This rare condition is further classified as primary or secondary lymphoma, depending on whether the disease is confined to the ciliary body or whether there is concomitant extensive systemic lymphoma (2)(3)(4)(5)(6)(7)(8). We herein report the clinical features, histopathological findings, systemic associations and treatment outcomes of three cases of ciliary body involvement by lymphoma with different primary lesions.…”

Section: Introductionmentioning

confidence: 99%

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Case Report: Ocular Manifestations and Treatments of Ciliary Body Involvement by Lymphoma

Han

et al. 2021

Front. Oncol.

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PurposeTo describe the ocular clinical features, histopathological findings, and treatment outcomes of lymphomas involving the ciliary body.MethodsWe demonstrate three cases of ciliary body involvement by lymphoma from 2013 to 2019 in Peking Union Medical College Hospital (PUMCH). All patients underwent examinations including best corrected visual acuity (BCVA), slit-lamp microscopy, indirect ophthalmoscope, ultrasound biomicroscopy (UBM), and diagnostic vitrectomy. In addition, cytopathology, immunohistochemistry, gene rearrangement, cytometric immunophenotypic, or in-situ hybridization were used for determining the pathological type of lymphoma.ResultsThe patients were a 25-year-old man, a 52-year-old woman, and a 54-year-old man. Two patients had unilateral involvement, and one patient had bilateral involvement. All patients presented with anterior uveitis and elevated intraocular pressure. Ciliary body masses or infiltration were found in 3 patients. Two patients had diffuse large B-cell lymphoma and one patient had natural killer/T-cell lymphoma. All patients received 0.4 mg methotrexate intravitreal injections, and the ciliary body lesions regressed completely.ConclusionLymphomatous involvement of the ciliary body usually presents as an atypical anterior chamber reaction. Vitreous biopsy should be considered in these patients for diagnosis. Methotrexate intravitreal injection combine with chemotherapy or radiotherapy, might extend the survival time and preserve visual acuity for patients with ciliary body involvement by lymphoma.

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“…The identification of lymphoma cells is considered the gold standard for the diagnosis of lymphomatous involvement of ciliary ( 5 ). Pei et al.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Case Report: Ocular Manifestations and Treatments of Ciliary Body Involvement by Lymphoma

Han

et al. 2021

Front. Oncol.

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show abstract

“…[ 1 ] Central nervous system (CNS) lesions are occasionally observed as sites of ENKL involvement, and extranodal involvement often leads to an unfavorable prognosis. [ 2 3 ] Here, a rare case of NL associated with ENKL that mainly presented as progressive multiplex painful mononeuropathy with multiple white matter lesions is reported.…”

mentioning

confidence: 99%

Neurolymphomatosis Caused by Nasal-type Extranodal Natural Killer/T-cell Lymphoma

Luo

Zhu

et al. 2017

Chinese Medical Journal

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A Case of Primary Central Nervous System Lymphoma with Ciliary Body Involvement

Cited by 2 publications

References 4 publications

Case Report: Ocular Manifestations and Treatments of Ciliary Body Involvement by Lymphoma

Case Report: Ocular Manifestations and Treatments of Ciliary Body Involvement by Lymphoma

Neurolymphomatosis Caused by Nasal-type Extranodal Natural Killer/T-cell Lymphoma

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