A case of primary squamous cell carcinoma of the parotid gland and review of the literature

Abstract

Introduction: Primary parotid squamous cell carcinoma (PPSCC) is a rare malignant epithelial tumor originating in the parotid gland with complex diagnostic procedures and a poor prognosis. The etiology, tissue origin, and biological behavior of the disease are currently unknown due to its underreporting. It is crucial to differentiate this type of squamous cell carcinoma (SCC) of the parotid gland from other salivary gland tumors because of its widespread invasiveness, which leads to high mortality. Case Report: This article reports a case of a 62-year-old male patient in whom histopathological examination confirmed that the tumor was squamous cell carcinoma. Since the patient had no other main source, the ultimate diagnosis was the primary SCC of the parotid gland. The patient is currently receiving routine follow-up care and has shown no signs of recurrence. Conclusion: In conclusion, even asymptomatic individuals should be highly regarded to prevent mistakes because the diagnostic process for this disease is complicated. The presence of metastatic cancer should be ruled out, and histology and immunohistochemistry should be used to confirm the diagnosis.