A case report: Acute neuromyelitis in pregnancy

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a demyleinating disease of the central nervous system. NMOSD is characterized by severe relapse of optic neuritis, longitudinal extensive myelitis and the presence of anti aquaporin-4 IgG (AQP4-IgG) in serum. Female factors like genetic, epi-genetic, or hormonal, may play an important role in pathogenesis. Female gonadal hormones, estrogen and progesterone, rise significantly during pregnancy, and decrease during the postpartum period. We are reporting a case of Gravida 2 Para1 Living1 Abortion 0 with full term with known case of acute neuromyelitis (on treatment for 3 years). Patient delivered vaginally, post natal period was uneventful.