A Case Report of Urinary Bladder Carcinosarcoma and Review of the Literature

Abstract

Carcinosarcoma of the bladder is an unusual tumour characterized by a combination of malignant epithelial and soft tissue elements. Most of the reported cases have been case reports or small series. Optimal treatment is uncertain. We herein report our experience in such a case treated with transurethral resection followed by radiotherapy with adverse final outcome. Treatment of bladder carcinosarcomas should be aggressive and multimodal but optional treatment is still unknown. Radiotherapy alone is insufficient as a treatment option of these aggressive tumors.

Urinary Bladder Carcinosarcoma (Sarcomatoid Carcinoma) With Long Survival After Transurethral Resection: A Case Report

“…A summary of recently reported bladder carcinosarcoma cases treated with transurethral resection is provided in Zachariadis et al have described an intriguing case of a 76-year-old female with a history of heart failure and diabetes treated with TUR-BT followed by radiation. However, the patient did not complete the protocol due to the progression of the disease and died five months later [17]. Hirano et al reported a 77-year-old patient diagnosed with urinary bladder carcinosarcomas and treated with TUR-BT alone and remained alive after 27 months of therapy without recurrence or metastasis [13].…”

“…However, poor treatment results in sarcomas are frequently attributed to advanced disease stages or poor patient health. Combining carboplatin and gemcitabine with irradiation has shown promising outcomes, while standard treatment frequently fails to react well to simple radiation therapy [7,17].…”

Bladder carcinosarcoma treated by cystectomy and adjuvant chemotherapy with good outcomes: a case report

“…The initial steps in the diagnostic and treatment strategy do not differ from the workup of other bladder tumors. Furthermore, cystoscopy remains the gold standard for diagnostic evaluation of hematuria and assessment of intravesical papillary masses [ 5 ].…”

Sarcomatoid Carcinoma of the Urinary Bladder: Case Report

“…Tedavide transüretral rezeksiyon, radikal sistektomi, radikal sistektomiyle birlikte radyoterapi, parsiyel sistektomi ve ameliyat sonrası radyoterapiyi takiben sistektomi şeklinde yöntemler uygulanmaktadır [9]. Mesanenin sarkomatoid karsinomları oldukça agresif tümörlerdir.…”