a case report on an intracranial solitary fibrous tumor

Abstract

Solitary fibrous tumors (SFT) are very rare, particularly those of the central nervous system (CNS), and they have mesenchymal origin. Here, we present the case of a 46-year-old man who, a year after suffering a head injury, lost consciousness for an hour. He had therapy after developing paralysis in his left arm and left foot after three months. A month and a half earlier, he had a bad headache, which triggered an examination. The right temporal frontal lesion on magnetic resonance imaging seems to be a sizable, well-defined extra-axial solid lesion with lobulated edges, predominantly isointense to the white matter with dispersed patches of hypointensity hole on T1WI. The lesion is isointense to the gray matter on T2WI, with sporadic hypointensities. Along the right anterior eminence with the bulk medially, thick, smooth dura mater is seen. A rise in the choline peak was seen in the MRI spectra. The right frontal lobe's white matter showed a little hyperintensity but no signs of angioedema-related diffusion limitation. The pathological diagnostic of the tumor was a grade 3 solitary fibrous tumor after it was surgically excised during a right frontal craniotomy with nearly an entire resection. S100, CD34, STAT Positivity for 6, CK, and KI67 were found during an immunohistochemistry study, and it was done since SFT is challenging to differentially detect through imaging. The patient had extra adjuvant therapy in the form of whole-brain external beam radiation (54 Gy/30#@1.8Gy/#@5#/week) due to the tumor's grade 3 status. Additional research and observation are needed for the prognosis.