A case report on drug rash with Eosinophiilia and systemic symptoms (DRESS) syndrome

Abstract

Background: DRESS syndrome is a distinctive, severe, and atypical drug reaction includes drug rash with eosinophilia and organ dysfunction symptoms, as well as hematological abnormalities. This disease is diagnosed using the Regis CAR (European Registry of Severe Cutaneous Adverse Reaction) scoring system. Case presentation: A 25-year-old lady presented with complaints of skin lesion over whole body since 3 days along with multiple clear fluid filled blisters over face and chin and lesions in oral cavity, multiple ill-defined areas of erythema with multiple bullae over face and chin. She also had complained about was also having cough, breathlessness and chest pain. Conclusion: DRESS syndrome is a severe hypersensitivity reaction caused by a reaction from drug, which in this case is found to be allopurinol. The treatment for the same is firstly the withdrawal of causative drug and using corticosteroids,in this patient dexamethasone was used.