“…In last years, the model-based HAZOP approach has been developed (Dimitriadis, Hackenberg, Shah, &Pantelides, 1996, Graf andSchmidt-Traub (2001), Eizenberg, Shacham, and Brauner (2006) and Srinivasan, Dimitriadis, Shah, and Venkatasubramanian (1997)). It is based on the description of a chemical plant using a mathematical model.…”