A case with two unusual findings: cutaneous leishmaniasis presenting as panniculitis and pericarditis after antimony therapy

Abstract

The histopathologic presentation of CL as panniculitis is a very rare and this is the first case of pericarditis after the antimony treatment.

Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence

“…Other studies report the treatment of 70 VL pregnant women with SbV. Among Pregnant (n = 17) 22-27,29 -38 Heart disease (n = 4) 9,61,71,72 Children (n = 14) 16,17,40 -51 Liver disease (n = 3) 9,73,74 Elderly (n = 8) [52][53][54][55][56][57][58][59] Immunosuppressed (n = 42) 62, Nursing mothers (n = 0) . Pentamidine isethionate should be avoided during pregnancy.…”

“…However, these changes are usually reversible after drug discontinuation. A case of pericarditis was reported in a CL patient treated with systemic meglumine antimoniate 72 .…”

Unusual presentation of cutaneous leishmaniasis

“…There are worldwide reports of unusual presentations of CL from different endemic countries: acute paronychial forms, fissure leishmaniasis, chancriform, annular, palmo-plantar, zosteriform, erysipeloid, lupoid, scar leishmaniasis, subcutaneous submandibular nodule, whitlow, discoid lupus erythematosus-like, squamous cell carcinoma-like, eczematous, verrucous, mucocutaneous and panniculitic variants. [5–11] The wide variation in the morphological presentation of CL has been attributed to many factors relating to the strain of the parasite, pathogenicity, virulence, infectivity, immunological status of the host and geographical factors of the place of dwelling. [27]…”

Cutaneous Leishmaniasis Mimicking A Pyogenic Granuloma

“…In a series of 57 cases of LC, confirmed by PCR, published in 2012 by Saab et al (7), other forms such as panniculitis (12), tuberculosis-like lesions, mycosis, anaplastic T-cell lymphoma, sarcoidosis, pityriasis lichenoides, indeterminate leprosy, subacute spongiotic dermatitis or lichen planus are described. However, we have not found any case of LC with an angiomatoid pattern in the reviewed publications.…”