A Chemo‐Mechanically Coupled DNA Origami Clamp Capable of Generating Robust Compression Forces
Chun Xie,
Kuiting Chen,
Zhekun Chen
et al.
Abstract:DNA nanostructures have been utilized to study biological mechanical processes and construct artificial nanosystems. Many application scenarios necessitate nanodevices able to robustly generate large single molecular forces. However, most existing dynamic DNA nanostructures are triggered by probabilistic hybridization reactions between spatially separated DNA strands, which only non‐deterministically generate relatively small compression forces (≈0.4 piconewtons (pN)). Here, an intercalator‐triggered dynamic D… Show more
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