A clinical and histopathologic study of granulomatous rosacea

Helm, Klaus F.; Menz, Jennifer; Gibson, Lawrence E.; Dicken, Charles H.

doi:10.1016/0190-9622(91)70304-k

Cited by 117 publications

(104 citation statements)

References 25 publications

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“…The role of Demodex in GR's pathogenesis was debated in the last decade, with recent data highlighting its significant role in triggering GR [3]. Our observation confirmed that this mite plays an important role in stimulation of the immune system and the formation of granulomas in GR in unusual sites.…”

Section: Discussionsupporting

confidence: 76%

Granulomatous Rosacea- A Case Report

2016

ARC Journal of Clinical Case Reports

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Background: Granulomatous rosacea is a rare chronic inflammatory skin disease with an unknown origin. The role of Demodex follicularum in its pathogenesis is currently proved. Case presentation: We report a case of a 54-year-old Moroccan man with a 3-month history of erythematous, nonpruritic papules on the lateral side around the eyes. Dermoscopy and histology confirmed the diagnosis of granulomatous rosacea. Conclusions: We describe another clinical presentation of granulomatous rosacea with a clinical-dermoscopicpathological correlation.

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Section: Discussionsupporting

confidence: 76%

Granulomatous Rosacea- A Case Report

2016

ARC Journal of Clinical Case Reports

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“…Lesions have been described as involving the ears, neck, axillae, trunk, and groin in granulomatous rosacea. 17 The major distinguishing features of granulomatous rosacea are the lack of a concentration of periorificial lesions and the association of erythema, telangiectasias, pustules, and edema, which are features of more typical rosacea. 17 Rosacea and granulomatous rosacea have been reported in children, but are uncommon.…”

Section: Commentmentioning

confidence: 99%

Extrafacial and Generalized Granulomatous Periorificial Dermatitis

Urbatsch¹,

Frieden²,

Williams³

et al. 2002

Arch Dermatol

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Background: Granulomatous periorificial dermatitis is a well-recognized entity presenting most commonly in prepubertal children as yellow-brown papules limited to the perioral, perinasal, and periocular regions. The condition is self-limiting and is not associated with systemic involvement.Observations: We reviewed the medical charts of 5 healthy children presenting with extrafacial granulomatous papules in addition to the typical periorificial papules. These extrafacial lesions were clinically and histologically identical to the facial lesions, were self-limiting, and were not associated with systemic involvement. Resolution seemed to be hastened with the use of systemic antibiotic therapy in 4 of the 5 patients.Conclusions: Extrafacial lesions can occur in granulomatous periorificial dermatitis and do not appear to adversely affect the duration, response to therapy, or risk of extracutaneous manifestations. Overly aggressive evaluation and inappropriate systemic therapy should be avoided.

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“…All patients had an adequate response to prednisone, coinciding with the literature reported, an additional reason to realize that this pathology is not related to tuberculosis, nor rosacea, because the patients had worsened [13]. For all the above mentioned, we agree with other authors in what was formerly called and considered as different pathologies like Disseminated lupus miliary of the face, acne agminata, and periorifical granulomatous dermatitis, all should be considered as a single pathology with different evolutionary aspects, and histological stages, under the term Idiopathic Facial Granulomas with regressive evolution [18].…”

Section: Commentarymentioning

confidence: 47%

“…Consequently, the terms acne agminata, and idiopathic facial granuloma with regressive evolution have replaced the term "disseminated lupus miliary of the face" in several parts of the world. However, this condition is not a variant of acne and does not always occur as repetitive outbreaks of injury, so the name acne agminata is also not appropriate [17][18][19]. It is important to bear in mind that what has led to this denomination are certain similarities with acne, such as the predominance of lesions in the central facial area, and even in extra facial areas like sebaceous glands in thorax, also the coexistence in many cases of pustular lesions and later scars ice pick like [19].…”

Section: Commentarymentioning

confidence: 99%

Facial Idiopathic Granulomas with Regressive Evolution, is Lupus Miliar Diseminatus Faciae a Synonymous?

Eg¹

2017

CDOAJ

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Disseminated lupus miliary of the face (DLMF) has been reported infrequently at the time that has received multiple denominations. It is clinically characterized by brown erythematous monomorphic papules of between 1 to 4 millimeters in diameter and icepick scars like acne.The cases presented in this document show the variability of presentation and manifestation of this pathology, the same that in certain occasions coincides with the previous reports, but also exist in others pathologists with a different presentation.Treatment with corticosteroids has shown improvement in lesions, coinciding with the reported literature.

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A clinical and histopathologic study of granulomatous rosacea

Cited by 117 publications

References 25 publications

Granulomatous Rosacea- A Case Report

Granulomatous Rosacea- A Case Report

Extrafacial and Generalized Granulomatous Periorificial Dermatitis

Facial Idiopathic Granulomas with Regressive Evolution, is Lupus Miliar Diseminatus Faciae a Synonymous?

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