2006
DOI: 10.1016/j.annemergmed.2005.08.007
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A Clinical Prediction Rule for Early Discharge of Patients With Chest Pain

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Cited by 116 publications
(120 citation statements)
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“…4 Greenslade et al's 5 study, which replaced CK-MB with troponin as the cardiac enzyme marker in the original VCP Rule, also reported higher sensitivity (91%) but similar NPV (94.4%) as our study. Specificity was higher in our study as compared to Christenson's 4 and Greenslade's 5 studies.…”
Section: Discussionsupporting
confidence: 76%
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“…4 Greenslade et al's 5 study, which replaced CK-MB with troponin as the cardiac enzyme marker in the original VCP Rule, also reported higher sensitivity (91%) but similar NPV (94.4%) as our study. Specificity was higher in our study as compared to Christenson's 4 and Greenslade's 5 studies.…”
Section: Discussionsupporting
confidence: 76%
“…4,6,7 The diagnosis of definite unstable angina in Christenson's study required rest pain greater than or equal to 20 minutes, and at least one of the following related to the presenting symptoms: 1) troponin increase 0.1 to 0.99 mg/L, 2) dynamic ECG changes consistent with ischemia in two contiguous leads (dynamic ST depression 0.5 mm or dynamic deep T-wave inversion), 3) a coronary angiogram with greater than 70% lesion plus hospital admission for ACS, or 4) a positive stress test result (radionuclide scan echo or ECG stress test) plus admission for ACS. 4 For our study, we have chosen to use proven adverse cardiac events as our main outcome measure, which we felt was more conservative and clinically important. Despite this, we note the relatively poorer performance of the rule in our population.…”
Section: Discussionmentioning
confidence: 99%
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