A Clinical Stain for Use in Selecting Biopsy Sites in Patients with Vulvar Disease

Collins, Conrad G.; Hansen, Lawrence H.; Theriot, E.

doi:10.1097/00003081-196608000-00003

Cited by 24 publications

(9 citation statements)

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“…It thus cannot be overemphasized that a meticulous visual examination of the external genitalia, coupled with a liberal biopsy of any suspicious areas, is the only means of detecting its lesions. Toluidine blue staining of the vulva may not be reliable as areas of fissures, cracks, and abrasions retain dyes, and a false positive rate of 17% has been reported [36]. To avoid this error, a colposcope could be used before and after staining [37].…”

Section: As Well As Condyloma Accumulata Viruses [ 131mentioning

confidence: 99%

Double primary epidermoid carcinoma of the vulva and cervix

Choo

Morley

1980

Gynecologic Oncology

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A retrospective study was undertaken on patients with multiprimaries associated with vulva carcinoma, analyzing in particular 33 patients with double epidermoid primaries of the vulva and cervix. It is noted that 20.8% of patients with vuivar carcinoma had a second primary; this occurred more frequently in intraepithelial (33.3%) than in invasive (16.0%) vulvar carcinoma. While the commonest second primary is located in the cervix, this association appears significant only in patients with intraepithelial (22.5%), but not in invasive (7.%), vulvar carcinoma. The incidences previously reported in the literature are also reviewed for comparison.

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Section: As Well As Condyloma Accumulata Viruses [ 131mentioning

confidence: 99%

Double primary epidermoid carcinoma of the vulva and cervix

Choo

Morley

1980

Gynecologic Oncology

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“…This view correlates with our finding that it "may be impossible to predict future malignant change by histological examination" (O'Flynn and Mullaney, 1967) in urinary bladder leukoplakia. Toluidine blue was used by Coliins, Hanson and Theriot (1966) for the detection of the onset of neoplasia in leukoplakia of the vulva: this might be a possible diagnostic aid in long-standing vesical cases, but has not been tried in this series.…”

Section: Discussionmentioning

confidence: 99%

Vesical Leukoplakia Progressing to Carcinoma

O'flynn

Mullaney

1974

British Journal of Urology

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“…Collins et al (1966) reported a high degree of accuracy using the toluidine blue stain to paint the vulva, then removing the stain not taken up by the unaffected tissues with acetic acid. The type of biopsy is not important, but the site of the biopsy is.…”

Section: Discussionmentioning

confidence: 99%

Simple Vulvectomy—A 10‐Year Review

Abell

1973

Aust NZ J Obst Gynaeco

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A review of 16 cases of simple vulvectomy performed at The Royal Women's Hospital in the 10-year period from 1959 to 1968 is presented. This operation finds its place in gynaecology following accurate and thorough diagnostic techniques, and close liaison between gynaecologist and pathologist. In some patients, simple vulvectomy affords the prime method of treatment, although in the majority it falls second to conservative attempts at management which have failed, particularly in the condition of lichen sclerosis et atrophicus.The reported high incidence of recurrence of pathology after simple vulvectomy was not confirmed.

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A Clinical Stain for Use in Selecting Biopsy Sites in Patients with Vulvar Disease

Cited by 24 publications

References 0 publications

Double primary epidermoid carcinoma of the vulva and cervix

Double primary epidermoid carcinoma of the vulva and cervix

Vesical Leukoplakia Progressing to Carcinoma

Simple Vulvectomy—A 10‐Year Review

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