A Clinical Study Showing Association of Serum Lipids With Primary Open Angle Glaucoma

Abstract

Introduction: Glaucoma, a multifactorial condition characterized by progressive optic neuropathy and distinctive visual eld loss, has become the most common cause of irreversible blindness worldwide. Many cases have shown progress despite of good control of IOP, strengthening the view that other independent risk factors play role in pathogenesis of glaucoma. Few studies have shown association of serum lipids to glaucoma. The objective of the study is to nd relation between serum lipid and POAG. Materials and Method: The study was conducted on 50 cases of glaucoma and 50 age matched controls. Detailed ophthalmic examinations were performed in all patients. Fasting lipid prole including total cholesterol, triglyceride, Low density lipoprotein(LDL),and high density lipoprotein (HDL) were measured and analyzed between the cases and controls. Result: Level of total cholesterol, total triglyceride, and LDLwere signicantly higher in cases than in contacts with Pvalue <0.05.Level of HDL was lowered in cases than in controls but it was not statistically signicant. Conclusion: Dyslipidemia is an independent risk factor for POAG. High serum Cholesterol, high triglyceride and high serum LDLcorrelate signicantly with POAG.