A Clinico-Pathological Survey of Thyroid Glands in Old Age

Denham, Melinda; Wills, E. J.

doi:10.1159/000212409

Cited by 41 publications

(20 citation statements)

References 14 publications

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“…The body of elderly people shows a decreased ability to adapt to changing environmental and intracorporeal conditions, which mainly results from the process of multiple organ involution, including the endocrine system [20,21]. The thyroid gland with increasing age changes its macroscopic and microscopic structure [20,21].…”

Section: Thyroid Glandmentioning

confidence: 99%

“…The thyroid gland with increasing age changes its macroscopic and microscopic structure [20,21]. Its glandular tissue gradually rebuilds.…”

Section: Thyroid Glandmentioning

confidence: 99%

“…W podeszłym wieku dochodzi do inwolucji wielu narządów, w tym układu dokrewnego [20,21]. Gruczoł tarczowy z wiekiem zmienia swój obraz makroskopowy i mikroskopowy [20,21].…”

Section: Tarczycaunclassified

“…Gruczoł tarczowy z wiekiem zmienia swój obraz makroskopowy i mikroskopowy [20,21]. Tkanka gruczołowa stopniowo przebudowuje się.…”

Section: Tarczycaunclassified

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The aging process and function of endocrine glands

Kazimierczak¹,

Nych²,

Marek³

et al. 2017

Ann. Acad. Med. Siles.

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Population aging is becoming the biggest medical challenge of the 21st century. The body of elderly people shows a decreased ability to adapt to changing environmental and intracorporeal conditions. Aging is a process that is complex and stretches over a considerable length of time. As we get older our bodies progressively change, including the endocrine system. The changes are not unidirectional and do not affect all the endocrine glands to the same degree. The secretion of some hormones becomes impaired, while the secretion of other ones increases. There are also some hormones whose secretion does not change. The frequent concomitance of chronic diseases and taking many medications makes it difficult to interpret the results of studies on changes in hormone secretion in elderly people. This paper focuses on aging-related changes in the secretion of growth hormone, thyroid hormones, parathyroid and adrenal hormones. K E Y W O R D Saging, somatopause, thyroid hormones, parathyroid glands hormones, adrenal gland hormones ST R ES ZCZ E N IEStarzenie społeczeństw staje się największym wyzwaniem medycznym XXI w. Organizm osób w podeszłym wieku wykazuje obniżoną umiejętność przystosowywania się do zmiennych warunków środowiska zewnętrznego i wewnętrznego. Starzenie to proces złożony i znacznie rozciągnięty w czasie. Wraz z wiekiem dochodzi do postępu-jących zmian w ustroju, w tym do zmian w układzie endokrynnym. Zmiany te nie są jednokierunkowe i nie dotyczą w równym stopniu wszystkich gruczołów dokrewnych. Wydzielanie części hormonów ulega upośledzeniu, innych

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Section: Thyroid Glandmentioning

confidence: 99%

“…The thyroid gland with increasing age changes its macroscopic and microscopic structure [20,21]. Its glandular tissue gradually rebuilds.…”

Section: Thyroid Glandmentioning

confidence: 99%

See 2 more Smart Citations

The aging process and function of endocrine glands

Kazimierczak¹,

Nych²,

Marek³

et al. 2017

Ann. Acad. Med. Siles.

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“…A MAIORIA DOS ESTUDOS PUBLICADOS concorda que, na população idosa, a prevalência de nódulos tiroideanos é nitidamente maior e tende a aumentar proporcionalmente com a idade (1)(2)(3)(4)(5). Por outro lado, relatos sobre o volume glandular em idosos são discordantes (1)(2)(3)(4)(5)(6)(7)(8). A controvér-sia existe devido a alguns fatores, como: nível de suficiência de iodo alimentar na região estudada, etnia e métodos usados para a detecção destas alterações (palpação, ultra-som ou exame anátomo-patológico) que podem interferir diretamente nos resultados.…”

Section: Introductionunclassified

Prevalência de bócio e nódulos tiroideanos detectados através de ultra-som em população com mais de 50 anos

Mendonça

Jorge

Diniz

2000

Arq Bras Endocrinol Metab

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RESUMOO objetivo deste trabalho foi estudar a prevalência de bócio e nódulos em uma população com mais de 50 anos, comparando-a com grupo controle composto pelos filhos. Para isso, foram avaliados 101 indivíduos (19M / 82 F) com idades entre 51 e 85 anos e 65 filhos (18 M / 47 F) com idades entre 14 e 50 anos. Utilizamos o ultra-som para diagnóstico de bócio e nódulos, mas foi feita, também, avaliação clínica com palpação da tiróide. A prevalência de bócio e nódulos foi maior nos indiví-duos com mais de 50 anos (15,8% e 18,8%, respectivamente), do que nos filhos (3,1% e 7,7%, respectivamente), Não observamos correlação entre volume tiroideano e idade. A palpação da tiróide se mostrou pouco sensível para detecção de bócio e nódulos, mas com alta especificidade. Concluímos que a prevalência de bócio e nódulos é maior na população com mais de 50 anos, embora sem correlação entre volume tiroideano e idade. O ultra-som se mostrou melhor que a palpação isoladamente, na detecção de alterações do volume e presença de nódulos tiroideanos. ABSTRACTThe aim of this study was to determine the prevalence of goiter and thyroid nodules in a population aged 50 years and older, matching with a younger control group, their offspring. We studied 101 subjects (19M/82F), 51 to 85 years and 65 offspring (18M / 47F), 14 to 50 years of age. Ultrasound was used to identify goiter and thyroid nodules, but all thyroids were also evaluated by palpation. The prevalence of goiter and thyroid nodules were higher in the older group (15.8% and 18.8%, respectively) as compared to their offspring (3.1% and 7,7%, respectively). No correlation was found between thyroid volume and age. Thyroid palpation has poor sensitivity but high specificity in identifying goiter and nodules. We conclude that goiter and nodules are more prevalent in the elderly, with no correlation between thyroid volume and age. Ultrasound was better than thyroid palpation to detect goiter and nodules. A MAIORIA DOS ESTUDOS PUBLICADOS concorda que, na população idosa, a prevalência de nódulos tiroideanos é nitidamente maior e tende a aumentar proporcionalmente com a idade (1-5). Por outro lado, relatos sobre o volume glandular em idosos são discordantes (1-8). A controvér-sia existe devido a alguns fatores, como: nível de suficiência de iodo alimentar na região estudada, etnia e métodos usados para a detecção destas alterações (palpação, ultra-som ou exame anátomo-patológico) que podem interferir diretamente nos resultados.

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Thyroid Surgery in the Geriatric Patient

Passler

Avanessian²,

Kaczirek³

et al. 2002

Arch Surg

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Background: Although age itself is no contraindication for major surgical procedures, few patients 75 years and older undergo thyroid surgery. Hypothesis: Thyroid surgery in the geriatric patient can be performed with low morbidity and mortality. Design: Retrospective analysis of prospectively documented data. Setting: University hospital referral center. Patients: We included 738 patients undergoing thyroid surgery within 5 years, of whom 55 (7.5%) were 75 years or older (group 1) (mean±SD age, 79.9±4.1 years). Main Outcome Measures: Indication for surgery, surgical strategy, morbidity, and mortality were analyzed and compared with those in younger patients (Ͻ75 years; group 2). Results: Malignancy was suspected or verified in 29 patients (52.7%) in group 1; 21 (38.2%) had mechanical symptoms due to large bilateral nodular goiters; and 5

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A Clinico-Pathological Survey of Thyroid Glands in Old Age

Cited by 41 publications

References 14 publications

The aging process and function of endocrine glands

The aging process and function of endocrine glands

Prevalência de bócio e nódulos tiroideanos detectados através de ultra-som em população com mais de 50 anos

Thyroid Surgery in the Geriatric Patient

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