A CN<sup>−</sup>specific turn-on phosphorescent probe with probable application for enzymatic assay and as an imaging reagent

Reddy, G Upendar; Das, Priyadip; Saha, Sukdeb; Baidya, Mithu; Ghosh, Sudip Kumar; Das, Amitava

doi:10.1039/c2cc37243f

Cited by 102 publications

(38 citation statements)

References 31 publications

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“…Notably, luminescent sensor 38 containing a Cu 2+ -DPA moiety incorporated into an Ir 3+ -polypyridyl luminophore is capable of cyanide detection in aqueous environments at concentrations lower than the standard safety limits, and in live cells pre-exposed to a 0.2 ppm aqueous cyanide solution [77]. Yoon and coworkers introduced sensor 39 for in vivo imaging using nematode C. elegans as the testing organism.…”

Section: Sensing Cyanide By Metal Displacementmentioning

confidence: 99%

Detection of Metal Ions, Anions and Small Molecules Using Metal Complexes

Wang

Franz

2014

Inorganic Chemical Biology

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Biology is a complex network of molecules that interact, organize, and communicate. We cannot readily visualize most of these species, and yet we are interested in tracking their presence within cells, tissues, or biological fluids in order to provide a deeper understanding of their physiological significance. There has been considerable effort, therefore, to develop chemical sensors that can "see" specific analytes in biological systems.A chemical sensor reports the presence of an analyte by converting a recognition event (usually, but not always, a binding event) into a spectroscopic signal. The analytes of interest include a broad swath of molecule types, including anions, reactive small molecules, proteins, nucleic acids, metal ions, or any other biological or foreign molecule. The spectroscopic signals can be colorimetric, luminescent, magnetic, electrochemical, or radioactive. Currently used sensors largely rely on organic dyes, fluorescent proteins, nanoparticles, and metal complexes for responsive signal transduction. In this chapter, we focus exclusively on the use of metal complexes as design features for chemical sensors. Subsets of this category include radiometals and electroactive metals, which are not covered further here. Instead, we direct interested readers to a recent comprehensive review of the coordination chemistry of radiometals and their application as probes in PET and SPECT imaging [1], as well as reviews on the use of electroactive transition metal receptors for electrochemical sensing applications [2,3].

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Section: Sensing Cyanide By Metal Displacementmentioning

confidence: 99%

Detection of Metal Ions, Anions and Small Molecules Using Metal Complexes

Wang

Franz

2014

Inorganic Chemical Biology

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“…Photochromic materials, in particular, are of considerable interest as the regulation of their activity using light allows both spatial and temporal control without any physical contact. Taking advantage of these unique properties, researchers are actively looking at the applications of photochromic materials in consumer devices, biomedical devices, electronics, and energy storage …”

Section: Introductionmentioning

confidence: 99%

Modulation of Electronic Mobility of a One‐Dimensional Coordination Polymeric Molecular Wire with Light

Saha

Chatterjee

Hossain

et al. 2019

Chemistry An Asian Journal

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Metal ions often influence the photoswitching efficiency of ap hotochromic system.T his article reports ao nedimensional polymer having cyclic azobenzenes coordinated to silver ions that are bridged by nitrates. The coordination polymer (CP-2)d isplays ap hotoresponsive behavior.T he switching ability in the polymer form was faster compared to the parenta zobenzene ligand withoutt he metal ions. Azobenzenes are reported to be poorlyc onducting. Here, although the azobenzene ligand does not show significant electronic mobility,t he coordination polymer (CP-2)d isplays am odest conductivity.T he conductance in the cis form of the polymer is significantly higher compared to the trans form. Upon exposure to visible light, the cis form undergoes photoisomerization to the trans form with ad rastic drop in the electronic mobility.T he trans form can be reverted to the cis form thermally or by using UV light.Thus,t his system offers ar eversible control of the conductivity using light.

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“…Reddy et al . successfully utilized the recognition of CN − ions using the Cu 2+ ensemble for bio‐imaging applications.…”

Section: Introductionmentioning

confidence: 99%

A Critical Review on Colorimetric and Fluorescent Probes for the Sensing of Analytes via Relay Recognition from the year 2012–17

2018

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Designing an effective sensor molecule for the selective detection of analyte with dual sensitivity is an innovative approach and is expected to offer huge biological and environmental benefits. Contrary to other sensing process, the reversible recognition of two different analytes while varying the binding sites and signaling subunits is entirely a new concept as the metal ion present in the ensemble can be easily displaced in the presence of ionic or neutral analytes. A reversible strategy can also be employed in the simultaneous recognition and identification of two different analytes with the aid of highly selective and sensitive chemosensors. This review gives an overview of the recent inventions (from 2012 to 2017) in the field of colorimetric and fluorescent receptors towards the detection of two analytes via a relay recognition process. A special emphasis is placed on different mechanisms associated with the sensing process assisted by fluorescence induced receptors which will help to design an effective sensor system for the selective detection of anions or amino acids or metal ions.

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A CN⁻specific turn-on phosphorescent probe with probable application for enzymatic assay and as an imaging reagent

Abstract: A new "turn-on" luminescence probe for imaging the uptake of 0.2 ppm inorganic CN(-) in live HeLa cells as well as for probing the CN(-) generation through an enzymatic process in a virtual aqueous medium at appropriate pH.

Cited by 102 publications

References 31 publications

Detection of Metal Ions, Anions and Small Molecules Using Metal Complexes

Detection of Metal Ions, Anions and Small Molecules Using Metal Complexes

Modulation of Electronic Mobility of a One‐Dimensional Coordination Polymeric Molecular Wire with Light

A Critical Review on Colorimetric and Fluorescent Probes for the Sensing of Analytes via Relay Recognition from the year 2012–17

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A CN−specific turn-on phosphorescent probe with probable application for enzymatic assay and as an imaging reagent

Abstract: A new "turn-on" luminescence probe for imaging the uptake of 0.2 ppm inorganic CN(-) in live HeLa cells as well as for probing the CN(-) generation through an enzymatic process in a virtual aqueous medium at appropriate pH.

Cited by 102 publications

References 31 publications

Detection of Metal Ions, Anions and Small Molecules Using Metal Complexes

Detection of Metal Ions, Anions and Small Molecules Using Metal Complexes

Modulation of Electronic Mobility of a One‐Dimensional Coordination Polymeric Molecular Wire with Light

A Critical Review on Colorimetric and Fluorescent Probes for the Sensing of Analytes via Relay Recognition from the year 2012–17

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Product

Resources

About

A CN⁻specific turn-on phosphorescent probe with probable application for enzymatic assay and as an imaging reagent