A code biology analysis of the regulatory regions in cell lines

Paredes, Omar; May-Canche, Isaias; Fimmel, Elena

doi:10.17488/rmib.40.1.11

Cited by 1 publication

(1 citation statement)

References 29 publications

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“…In Paredes et al ( 2018 ), we explored the way biological phenomena are encoded not only within the genome's coding regions but also in their interactions with non-coding ones. Therefore, we stated the possibility to evidence that the genomic syntax's behavior includes those non-coding genomic regions.…”

Section: Minimal Genomementioning

confidence: 99%

Decoding semiotic minimal genome: a non-genocentric approach

Gómez-Márquez,

Morales,

Romero-Gutiérrez

et al. 2024

Front. Microbiol.

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The search for the minimum information required for an organism to sustain a cellular system network has rendered both the identification of a fixed number of known genes and those genes whose function remains to be identified. The approaches used in such search generally focus their analysis on coding genomic regions, based on the genome to proteic-product perspective. Such approaches leave other fundamental processes aside, mainly those that include higher-level information management. To cope with this limitation, a non-genocentric approach based on genomic sequence analysis using language processing tools and gene ontology may prove an effective strategy for the identification of those fundamental genomic elements for life autonomy. Additionally, this approach will provide us with an integrative analysis of the information value present in all genomic elements, regardless of their coding status.

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Section: Minimal Genomementioning

confidence: 99%