A colorimetric and ratiometric fluorescent probe with a large stokes shift for detection of hydrogen sulfide

A colorimetric and ratiometric fluorescence probe for rapid detection of SO 2 derivatives bisulfite and sulfite

“…Enlightened by this addition reaction, we hope that this reaction could be served as the foundation to design a novel fluorescence probe. Herein, we focused our attention on semi-cyanine-coumarin hybrid dyes because these dyes have typical donor-π-acceptor (D-π-A) structure, longer emission wavelength in the red (or NIR) region, and large Stokes shift from the ultrafast intramolecular charge transfer (ICT) [36][37][38][39][40][41][42][43]. In addition, this type of dyes is difficult to be inactivated in the presence of biothiols compared with other common Michael receptors [44].…”

Cyano Derivatives of 7‐Aminoquinoline That Are Highly Emissive in Water: Potential for Sensing Applications

“…Considering complex biological species and/or inorganic anions in tissue that may influence the analytic result, the sensing specificity is essential for a probe. [25][26][27][28][29][30][31][32] Accordingly, a test of selectivity was performed by the use of a variety of biomolecules and anions which may have potential to react with 6CNÀ 7N 3 Q and 3CNÀ 7N 3 Q. The results shown in Figure 3 and Figure S32 clearly reveal that the fluorescence of 6CNÀ 7N 3 Q and 3CNÀ 7N 3 Q is only observed in the presence of Na 2 S solution (200 μM), while cysteine, glutathione (GSH), lipoic acid and many other anions, in sharp contrast, do not respond to both 6CNÀ 7N 3 Q and 3CNÀ 7N 3 Q.…”

Hydrogen sulfide sensing using an aurone-based fluorescent probe

“…11 Thanks to its high sensitivity, rapid response, and generally simple sample preparation, uorescence spectroscopy has become the most common approach for the design of new hydrogen sulde sensors. Within these sensors, several different approaches have been developed, particularly the reduction of nitro and azido groups, [12][13][14][15][16][17][18][19][20][21][22] the chelation with copper (II) complexes, [23][24][25] nucleophilic thiolysis, [26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] and conjugate additions and cyclizations. [41][42][43][44][45] For all of these approaches, one key consideration is avoiding reaction with other common sulfur-containing compounds, particularly glutathione and cysteine.…”