A colorimetric hydrogel biosensor for rapid detection of nitrite ions

Nam, Jihye; Jung, In-Bok; Kim, Boyoon; Lee, Sang-Myung; Kim, Seong‐Eun; Lee, Kook-Nyung; Shin, Dong‐Sik

doi:10.1016/j.snb.2018.04.171

Cited by 107 publications

(39 citation statements)

References 36 publications

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“…Similar report can also be found in other research. [654,[657][658][659] In recent years, polymer-based hydrogel solid-phase extraction (SPE) was also used as sampling method in direct onsite fast screening of risk substances, such as mercury (II) (Hg 2+ ) ions, [660] illicit additives on fruit peel, [658] rhodamine B, [661] etc.…”

Section: Risk Monitoringmentioning

confidence: 99%

Hydrogel: Diversity of Structures and Applications in Food Science

Jia

Luo

2021

Food Reviews International

115

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Hydrogels are a series of soft and wet materials with three dimensions of crosslinked networks. Hydrogels have attracted great attention due to their diverse functional properties, and their wide range of applications, such as in soft robots and actuators, stretched electronic devices, tissue engineering materials, controlled-release drug delivery vehicles, biomedicine materials, food science, and (bio)sensors. In general, there are four core concerns in hydrogel science, including the polymer source, structure fabrication, gel function, and gel applications. According to the logic that the "structure determines function", it is believed that rational design of structures can effectively regulate the functions and applications of hydrogels. Hence, in the current review, "structure" as the core topic will be highly regarded, and the crosslinking mechanisms and structural diversity of hydrogels are comprehensively summarized. Additionally, hydrogels also show their great application potential in food science. Hence, the current review also pays more attention to the application of hydrogels in food nutrition and health, food engineering and processing, and food safety. It is whished that this review not only serves as a reference for improving the comprehensive understanding of the structural design of hydrogels but also provides a forward-looking idea for hydrogel applications in food science.

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Section: Risk Monitoringmentioning

confidence: 99%

Hydrogel: Diversity of Structures and Applications in Food Science

Jia

Luo

2021

Food Reviews International

115

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“…Tests in different ions concentration and pH were realized showing a good sensitivity, stability and high selectivity of the fabricated sensor. Naked-eye sensor can be very useful in a wide range of applications [46]. Ozay and co-authors in 2013 proposed a reusable naked-eye hydrogel sensor for ions [47].…”

Section: Ph Ions and Ionic Strength Sensorsmentioning

confidence: 99%

Progress in hydrogels for sensing applications: a review

Pinelli

Magagnin

Rossi

2020

Materials Today Chemistry

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There are several developments taking place in the field of sensors driven by the world today requirements. One of the most important novelties of the last two decades in the field is represented by the hydrogel-based sensors which constitute a wide family of innovative smart sensing devices relevant for many different applications. Hydrogels in fact are hydrophilic, biocompatible and highly water swellable polymer networks able to convert chemical energy into mechanical energy, with the great peculiarity to be able to respond to external stimuli. These characteristics have ensured them considerable recognition as valuable tool for smart sensing and diagnostics. The aim of this review is to focus on the advances obtained in the field in the last ten years.

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“…Recently, in order to detect biomolecules with high sensitivity, a number of novel sensing approaches have been developed by using colorimetry [ 15 , 16 ], fluorescence, SERS [ 17 , 18 ], electrochemical [ 19 , 20 ], and surface plasmon resonance (SPR) [ 21 , 22 ]. Each platform has its specific advantages, but it is still challenging to solve the problem of false negative detection, which is extremely important in epidemic prevention and control.…”

Section: Introductionmentioning

confidence: 99%

Rapid and sensitive triple-mode detection of causative SARS-CoV-2 virus specific genes through interaction between genes and nanoparticles

Gao

Han

Wang

et al. 2021

Analytica Chimica Acta

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The recent outbreak of coronavirus disease 2019 (COVID-19) is highly infectious, which threatens human health and has received increasing attention. So far, there is no specific drug or vaccine for COVID-19. Therefore, it is urgent to establish a rapid and sensitive early diagnosis platform, which is of great significance for physical separation of infected persons after rapid diagnosis. Here, we propose a colorimetric/SERS/fluorescence triple-mode biosensor based on AuNPs for the fast selective detection of viral RNA in 40 minutes. AuNPs with average size of 17 nm were synthesized, and colorimetric, surface enhanced Raman scattering (SERS), and fluorescence signals of sensors are simultaneously detected based on their basic aggregation property and affinity energy to different bio-molecules. The sensor achieves a limit detection of femtomole level in all triple modes, which is 160 fM in absorbance mode, 259 fM in fluorescence mode, and 395 fM in SERS mode. The triple-mode signals of the sensor are verified with each other to make the experimental results more accurate, and the capacity to recognize single-base mismatch in each working mode minimizes the false negative/positive reading of SARS-CoV-2. The proposed sensing platform provides a new way for the fast, sensitive, and selective detection of COVID-19 and other diseases.

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A colorimetric hydrogel biosensor for rapid detection of nitrite ions

Cited by 107 publications

References 36 publications

Hydrogel: Diversity of Structures and Applications in Food Science

Hydrogel: Diversity of Structures and Applications in Food Science

Progress in hydrogels for sensing applications: a review

Rapid and sensitive triple-mode detection of causative SARS-CoV-2 virus specific genes through interaction between genes and nanoparticles

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