Monitoring and assessing coastal subsidence is crucial to mitigating potential disaster risks associated with rising sea levels. Nansha District in Guangzhou City, representing global coastal soft-soil urban areas, faces significant challenges related to ground subsidence. However, the current understanding of the status, causative factors, and risk (includes subsidence susceptibility and vulnerability) assessment of ground subsidence in Nansha District is unclear. To address this gap, we utilized the SBAS-InSAR technique, analyzing 49 Sentinel-1A images from December 2015 to June 2019, for systematic ground subsidence monitoring. Subsequently, we assessed subsidence risk using a comprehensive index method and a risk matrix. Our findings indicate that subsidence velocity primarily ranged from −40 to −5 mm/a, with a spatial pattern of increasing subsidence from inland to coastal areas. The cumulative subsidence process unfolded in four distinct stages. The genesis of land subsidence was linked to an endogenous geological context dominated by soft-soil deposition, influenced by external factors such as surface loading and groundwater extraction. High-risk zones were concentrated in key engineering development areas, transportation pipeline trunk lines, and densely populated regions, demanding special attention. This study provides a foundational resource for disaster prevention and control strategies in Nansha District and similar coastal cities.