A Comparative Evaluation of Serum and Salivary Total Proteins and Immunoglobulins in Patients with Hepatitis A and Healthy Subjects

Abstract

Assessment of changes in total proteins level, serum and saliva IgG and IgA levels, serum IgM level, serum and saliva IgA/IgG ratio. The study was conducted on a group of 40 subjects, divided into 2 lots: the first lot consisting of 20 healthy individuals and the second consisting of 20 patients with hepatitis with hepatitis A virus (HAV). The levels of total proteins, serum and saliva IgG and IgA, serum IgM and serum and saliva IgA/IgG ratio have higher values in patients with hepatitis A, in comparison to healthy subjects, without necessarily exceeding the maximum admitted value. The results are significant from a statistical point of view. Due to the sensitivity and specificity of salivary anti-HAV IgM and IgG in patients with acute hepatitis A, compared with healthy subjects, there is a possibility of using salivary immunological tests instead of serum tests for the diagnosis and epidemiological study of HAV infection.

The Effects of Caffeine Intake on Cardiovascular Parameters in Sleep Deprived Medical Residents

“…Caffeine is a widely consumed stimulatory substance worldwide; its metabolite, paraxanthine is excreted in urine but also in saliva [10]. The ability of caffeine to inhibit adenosine receptors is highly important for its effects on behaviour and cognitive function.…”

Analyze of Saliva Cortisol as Biomarker in Healthy Distressed Subjects

“…The measurement of salivary cortisol is a noninvasive technique very often used in the study of cortisol secretion patterns in young subjects. Saliva measurements are relevant for several pathologies [8,9,10], while salivary cortisol and the serum cortisol correlate significantly. Reported values in clinically healthy adults lie between 0.94-15.51ng /dL (in women between 21 and 30 years) and between 2.72-13.48 ng /dL (in men aged 21-30) [10,11].…”