A Comparative Evaluation of Single Dose Transdermal Patch of Diclofenac Versus Ketoprofen for Post Operative Analgesia in Abdominal Hysretectomy.

Abstract

Introduction: Transdermal patch is very simple and painless method for providing postoperative analgesia. The aim of the study was to compare the efficacy and safety of transdermal patch of ketoprofen in comparion to diclofenac for post operative analgesia. It is randomized observational study. Method: Thirty six patients of 18 to 60 years were randomly allocated to receive either ketoprofen or diclofenac transdermal patch at the end of surgery under spinal anaethesia. Stastical analyasis used, data were analysed using statistical package for social sciences version 15.0 and open EPI software version 2.3. The primary end point is VAS score and total requirement of rescue analgesic first 24 hours of surgery. The secondary end points are time to rescue analgesic and adverse effects like nausea and vomiting. Conclusion: Single dose transdermal patch of Ketoprofen provided better post operative analgesia as compared to diclofenac sodium patch in abdominal hysterectomy (infraumblical surgeries) and less number of patients required rescue analgesia in ketoprofen group.