A Comparative Evaluation on Antimicrobial Effect of Honey, Neem Leaf Extract and Sodium Hypochlorite as Intracanal Irrigant: An Ex-Vivo Study

Sundaram, Divya; Narayanan, Retna Kumari; Vadakkepurayil, Kannan

doi:10.7860/jcdr/2016/19268.8311

Cited by 17 publications

(18 citation statements)

References 8 publications

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“…mutans and Lactobacilli species (Chava, Manjunath, Rajanikanth, & Sridevi, ; Pai, Acharya, & Udupa, ). Similar results were obtained using bark and twigs of the tree (Chaurasia, ; Geethashri, Manikandan, Ravishankar, & Shetty, ; Sundaram, Narayanan, & Vadakkepurayil, ). Moreover, nonabsorbable A .…”

Section: Pharmacological Attributessupporting

confidence: 77%

“…The combination of leaves extract with mucoadhesive dental gel formulation (25 mg/g) had depicted reasonable antimicrobial potential against S. mutans and Lactobacilli species (Chava, Manjunath, Rajanikanth, & Sridevi, 2012;Pai, Acharya, & Udupa, 2004). Similar results were obtained using bark and twigs of the tree (Chaurasia, 2016;Geethashri, Manikandan, Ravishankar, & Shetty, 2014;Sundaram, Narayanan, & Vadakkepurayil, 2016). Moreover, nonabsorbable A. indica oil chip (10%) showed significant antibacterial properties against Porphyromonas gingivalis, a periodontal pathogen (Vennila, Elanchezhiyan, & Ilavarasu, 2016).…”

Section: Antibacterial Activitymentioning

confidence: 60%

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A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

Saleem

Muhammad

Hussain

et al. 2018

Phytotherapy Research

128

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Azadirachta indica L. is a multipurpose medicinal tree of family Meliaceae. It occurs in tropical and semitropical regions of the world. Different parts of this miraculous tree are used to treat pyrexia, headache, ulcer, respiratory disorders, cancer, diabetes, leprosy, malaria, dengue, chicken pox, and dermal complications. The tree is popular for its pharmacological attributes such as hypolipidemic, antifertility, microbicidal, antidiabetic, anti-inflammatory, hepatoprotective, antipyretic, hypoglycemic, insecticidal, nematicidal, antiulcer, antioxidant, neuroprotective, cardioprotective, and antileishmaniasis properties. A. indica is also rich in various phytochemicals for pharmaceuticals such as alkaloids, steroids, flavonoids, terpenoids, fatty acids, and carbohydrates. The fungicidal potential of the tree is due to the presence of azadirachtin and nimbin. Herein, we have compiled a comprehensive review of phytochemical profile, pharmacological attributes, and therapeutic prospective of this multipurpose tree.

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Section: Pharmacological Attributessupporting

confidence: 77%

Section: Antibacterial Activitymentioning

confidence: 60%

A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

Saleem

Muhammad

Hussain

et al. 2018

Phytotherapy Research

128

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show abstract

“…In literature, there are many studies that have shown the remarkable biocompatibility of honey‐based extracts against different human cell lines (Sundaram et al . ), also at high concentrations (Sarhan and Hassan ). Even if the investigation regarding cytotoxic effects of honey against invertebrates is still limited, applications of honey extracts in aquaculture, such as in promoting growth and preservation of several freshwater fish species (Ferreira et al .…”

Section: Resultsmentioning

confidence: 98%

Italian acacia honey exhibits lytic effects against the crayfish pathogensAphanomyces astaciandFusarium avenaceum

Sateriale

Scioscia

Colicchio

et al. 2018

Lett Appl Microbiol

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Significance and Impact of the Study: The continuous spread of aquatic fungal disease as the 'crayfish plague' and the 'burn spot disease' has severe ecological and commercial repercussions. Critical factor to prevent further spread is the availability of effective antifungals possibility derived from local natural resources to use in innovative strategies of control and eradication of these diseases. This study provides relevant information about the in vitro anti-oomycete and antifungal activity of Italian acacia honey aqueous extracts against two highly infectious and dangerous pathogenic species, Aphanomyces astaci and Fusarium avenaceum, that are responsible for important crayfish diseases. AbstractThis study purpose was to evaluate the in vitro inhibitory properties of Italian acacia honey extracts against pathogenic aquatic oomycete/fungal isolates that cause different diseases in crayfish, resulting in an elevated mortality rate. The antimycotic activity of acacia honey aqueous extracts was evaluated against the strain UEF88662 of Aphanomyces astaci (oomycete) and the strain SMM2 of Fusarium avenaceum (fungus). The extracts preparation was carried out with water by a cheap, not complex and organic solvent-free procedure, with low environmental impact and the higher possibility of large-scale reproducibility. The anti-oomycete and antifungal activities were quantitatively evaluated by growth, survival and sporulation microbiological assays. The extracts displayed a dose-dependent inhibitory efficacy on oomycete and fungal growth and survival, as well as on the production of oomycete and fungal spores. Supported by future in vivo studies, our results encourage the use of natural extracts like honey as innovative tools to counteract mycotic infections.Letters in Applied Microbiology 68, 64--72

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“…Therefore, these can be used as root canal irrigating solutions. Sundaram et al [22] and Prasad et al [23] in 2016 also tested the herbal irrigants including neem for their antibacterial efficacy and had suggested its potential role in the future of endodontics.…”

Section: Rationale Of Using Neem As Endodontic Irrigantmentioning

confidence: 99%

Neem: a magical herb in endodontics

Singh¹,

Kaur²,

Dhillon³

et al. 2017

SDS

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A Comparative Evaluation on Antimicrobial Effect of Honey, Neem Leaf Extract and Sodium Hypochlorite as Intracanal Irrigant: An Ex-Vivo Study

Cited by 17 publications

References 8 publications

A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

Italian acacia honey exhibits lytic effects against the crayfish pathogensAphanomyces astaciandFusarium avenaceum

Neem: a magical herb in endodontics

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