A comparative phytochemical and pharmacological analysis of the extracts from leaves of the ukrainian flora shrubs

Blyznyuk, Nataliya; Prokopenko, Yu. S.; Georgiyants, V. A.; Tsyvunin, Vadim

doi:10.24959/nphj.16.2099

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…Anticonvulsant activity was studied by [ 40 ] in extracts from leaves of the Ukrainian flora shrubs showing that Corylus avellana dry aqueous extract can be a promising substance with anticonvulsant properties. Avocado leaf extract also was reported having anticonvulsant activity [ 17 ].…”

Section: Fruits Species and Their Medicinal Properties: An Updatementioning

confidence: 99%

Fruits as Prospective Reserves of bioactive Compounds: A Review

Karasawa

Mohan

2018

Nat. Prod. Bioprospect.

134

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Bioactive natural products have always played a significant role as novel therapeutical agents irrespective of their source of origin. They have a profound effect on human health by both direct and indirect means and also possess immense medicinal properties. Fruit species are largely appreciated and highly consumed throughout the world. Epidemiologic information supports the association between high intake of fruits and low risk of chronic diseases. There are several biological reasons why the consumption of fruits might reduce or prevent chronic diseases. Fruits are rich sources of nutrients and energy, have vitamins, minerals, fiber and numerous other classes of biologically active compounds. Moreover, parts of the fruit crops like fruit peels, leaves and barks also possess medicinal properties and have been included in this review. The most important activities discussed in this review include antidiabetic, anticancer, antihypertensive, neuroprotective, anti-inflammatory, antioxidant, antimicrobial, antiviral, stimulation of the immune system, cell detoxification, cholesterol synthesis, anticonvulsant and their ability to lower blood pressure. Several phytochemicals involved in this context are described with special emphasis on their structural properties and their relativity with human diseases.

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Section: Fruits Species and Their Medicinal Properties: An Updatementioning

confidence: 99%

Fruits as Prospective Reserves of bioactive Compounds: A Review

Karasawa

Mohan

2018

Nat. Prod. Bioprospect.

134

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“…The synergistic effect of biologically active compounds occurring in leaves of C. avellana collected in Ukraine has been invoked to explain the high anticonvulsant properties shown by the dry aqueous extract [71]. In fact, in mice subjected to pentylenetetrazoleinduced seizures the aqueous extract of hazelnut leaves, as well as the reference drug sodium valproate, showed the most pronounced anticonvulsant activity respect to the other hydroalcoholic extracts tested, resulting in a significant increase in the latency period of the first seizure occurrence, reducing lethality and duration of the convulsive period in the group.…”

Section: Anticonvulsant Propertiesmentioning

confidence: 99%

Plant Specialized Metabolites in Hazelnut (Corylus avellana) Kernel and Byproducts: An Update on Chemistry, Biological Activity, and Analytical Aspects

et al. 2019

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Corylus avellana (hazelnut) is one of the most popular tree nuts on a worldwide basis. The main products of C. avellana are kernels, a nutritious food, with a high content of healthy lipids, contained in a hard shell. In recent years, along with the ongoing research carried out on hazelnut kernels, a growing interest has been addressed to the hazelnut byproducts including hazelnut skin, hazelnut hard shell, and hazelnut green leafy cover as well as hazelnut tree leaf. These byproducts deriving from the roasting, cracking, shelling/hulling, and harvesting processes have been found as a source of “phytochemicals” with biological activity. The aim of this review is to provide a comprehensive and critical update on the chemistry and biological activity of specialized metabolites occurring in hazelnut kernels and byproducts. Phenolics are the most abundant phytochemicals not only in the kernels, but also in other processing byproducts. Attention has been also devoted to taxane derivatives isolated from C. avellana leaves. An overview on the biological activity, mainly antioxidant, antiproliferative, and antimicrobial along with less common biological effects, has been provided, contributing to highlight C. avellana as a source of bioactive phytochemicals with the potential to exert beneficial effects on human health. Finally, analytical techniques for the quali-quantitative analysis of specialized metabolites occurring in the different parts of C. avellana have been reviewed.

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A comparative phytochemical and pharmacological analysis of the extracts from leaves of the ukrainian flora shrubs

Abstract: In the Ukrainian flora such plants as Forsythia europaea Deg. et

Cited by 2 publications

References 2 publications

Fruits as Prospective Reserves of bioactive Compounds: A Review

Fruits as Prospective Reserves of bioactive Compounds: A Review

Plant Specialized Metabolites in Hazelnut (Corylus avellana) Kernel and Byproducts: An Update on Chemistry, Biological Activity, and Analytical Aspects

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