Abstract:The long‐acting local anaesthetics bupivacaine and etidocaine were compared in a double‐blind study using ulnar nerve block. Eleven volunteers took part in the study. Solutions used were: bupivacaine 0.25 % and 0.5 % and etidocaine 0.5 % and 1 %. All solutions contained adrenaline 5 μg/ml.
The time of onset and duration of analgesia and motor block, degree of motor block, and changes in skin temperature were investigated.
The results did not show any differences in the duration of sensory of motor block. Diffe… Show more
IQB-9302 is a new local anesthetic that has shown a long duration of action and low cardiovascular toxicity in preclinical studies. We report the results of a phase I clinical trial to compare this new drug with bupivacaine for ulnar nerve block.
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