A Comparative Study of Fluoride Containing Chlorhexidine and Non-Chlorhexidine Mouthrinses in a Teenage Group

Abstract

Aim: The study was planned to assess the effect of a mouthrinse containing Chlorhexidine (CHX) and amine/stannous fluoride (AmF) on plaque accumulation, gingivitis and salivary fluoride levels in comparison with two mouthrinses containing either essential oils (EO) or cetylpyridinium chloride (CPC) with sodium fluoride (NaF) in a teenage group. Methodology: For this study 82 healthy teenage between 13 and 16 years were recruited for participation. The experimental gingivitis model consisted of a 2-weeks recruitment phase, followed by a 6-day rinsing period with one of the 4 mouthrinse formulations was used for the study. At the end of the pre-phase period and the rinsing period (Day-0/Day-6), gingival index (GI), plaque index (PI) and salivary fluoride levels were recorded. The statistical analyses were performed using Wilcoxon sign test and the dependent t test.

Comparative effect of fluoride, essential oil and chlorhexidine mouth rinses on dental plaque and gingivitis in patients with and without dental caries: a randomized controlled trial

“…The removal of bacterial biofilm is a decisive component in the prevention and treatment of these diseases. Because of the difficulty to ensure adequate removal of plaque by mechanical means, there is a great interest in the use of antimicrobial agents to replace or to be adjuncts to the mechanical approaches . Mouthwashes, a safe and effective delivery system for antimicrobials, have been evaluated for antiplaque properties and have been the subject of considerable research.…”