A Comparative Study of Infusion Dexmedetomidine and Infusion Magnesium Sulphate on Attenuation of Blood Pressure Surge in Laparoscopic Surgery Under General Anaesthesia
Abstract:BACKGROUND The haemodynamic surge in laparoscopic surgery following carbon dioxide insufflations can be attenuated by various drugs. Dexmedetomidine, a selective-alpha-agonist depresses central sympathetic outflow producing sedation, decreased analgesic requirement, is approved by USFDA for mechanically ventilated patients in ICU for a period of <24 hours. One of its "off label" uses is attenuation of Hemodynamic changes in laparoscopic surgery. Parenteral magnesium sulphate has been used as an antiarrhythmic … Show more
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