A Comparative Study of Polydioxanone and Nylon for Abdominal Wall Closure With Interrupted Figure of Eight in Peritonitis Cases

Singal, Rikki; Kumar, Mohinder; Kaushik, Nitin; Dhar, Siddharth; Singh, Bir

doi:10.14740/jcs306e

Cited by 4 publications

(6 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…7,8,[12][13][14][15] It is quite evident that suture sinus formation frequently occurs with non-absorbable sutures like nylon/ prolene because of its long memory, stiff nature and tissue reactivity. The present study observed that suture sinus formation is more prevalent with prolene (5.9%) and this was consistent with findings of the studies conducted by Singal et al, Bloeman et al and Gaikwad et al 7,10,11 Present study demonstrated the incisional hernia rate as 3.1% in PDS group and 14.7% in prolene group (p>0.05). This is not in consonance to study done by Bloeman et al which showed the rate of incisional hernia to be more…”

Section: Discussionsupporting

confidence: 92%

“…Studies conducted by Israelsson et al and Van't et al also found similar results. 8,9 The wound discharge rate was 28.1% in PDS group while 26.5% in the prolene group (p>0.05) This was consistent with the results of the studies conducted by Singal et al, Bloeman et al and Gaikwad et al 7,10,11 More number of patients suffered from abdominal wound dehiscence in the PDS group but this was found to be statistically insignificant. But Gaikwad et al reported contrary findings with the PDS group, which showed a very high incidence of wound dehiscence, which has not been reported in any previously performed study.…”

Section: Discussionsupporting

confidence: 88%

See 1 more Smart Citation

Which suture is ideal for abdominal fascial closure: polydioxanone or polypropylene?

et al. 2023

View full text Add to dashboard Cite

Background: A secured fascial closure with appropriate suture material is an integral step to prevent complications in laparotomy. A costly post-operative complication is wound dehiscence which manifests as incisional hernia as a delayed complication. The present study compared prolene and polydioxanone (PDS) sutures in patients undergoing midline closure after emergency exploratory laparotomy with the aim to evaluate wound outcome after the use of either of the sutures. Methods: Sixty-six patients undergoing emergency laparotomy were randomly divided into two groups: group A (PDS) and B (prolene). Wound complications were evaluated for each patient in terms of wound pain, wound discharge, burst abdomen, stitch sinus, stitch granuloma and incisional hernia. Results: Wound pain was observed more in prolene group, p<0.05 till 3rd post-op day. Wound discharge, wound dehiscence and burst abdomen were more in prolene group, but the difference was statistically insignificant (p>0.05). Six patients developed incisional hernia, out of which 5 had prolene, (p>0.05). Similar statistically insignificant difference was found with stitch granuloma and stitch sinus. Conclusions: Till date there is lack of agreement about the ideal suture for abdominal fascial closure. Present study concluded that any suture material is equally effective for abdominal fascial closure since there are many other factors contributing towards wound complications.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 88%

Which suture is ideal for abdominal fascial closure: polydioxanone or polypropylene?

et al. 2023

View full text Add to dashboard Cite

show abstract

“…As with any new medical device, the biological evaluation of the device and material constituents must be carefully assessed. Polydioxanone—the polymer used for filament manufacture, was selected on the basis of history of safe clinical use [17, 52, 53]. Addition of pyridine into the polymer solution must be carefully considered within the framework of the wider biological evaluation, which is guided by ‘ISO 10993 Biological evaluation of medical devices’ and a risk based approach must be adopted to the use of any additional raw materials (including solvents and controlled impurities).…”

Section: Discussionmentioning

confidence: 99%

Pyridine as an additive to improve the deposition of continuous electrospun filaments

et al. 2019

View full text Add to dashboard Cite

Electrospun filaments are leading to a new generation of medical yarns that have the ability to enhance tissue healing through their biophysical cues. We have recently developed a technology to fabricate continuous electrospun filaments by depositing the submicron fibres onto a thin wire. Here we investigate the influence of pyridine on the fibre deposition. We have added pyridine to polydioxanone solutions at concentrations ranging from 0 to 100 ppm, increasing the conductivity of the solutions almost linearly from 0.04 uS/cm to 7 uS/cm. Following electrospinning, this led to deposition length increasing from 1 cm to 14 cm. The samples containing pyridine easily underwent cold drawing. The strength of drawn filaments increased from 0.8 N to 1.5 N and this corresponded to a decrease in fibre diameter, with values dropping from 2.7 μm to 1 μm. Overall, these findings are useful to increase the reliability of the manufacturing process of continuous electrospun filaments and to vary their biophysical properties required for their application as medical yarns such as surgical sutures.

show abstract

“…The rate of postoperative surgical site infection remains high at 3-20%, making it the most important early postoperative complication of midline laparotomy (incisional hernia is reported at 15% after open abdominal surgery, wound dehiscence at 0.5-3.4% and wound sinus at between 0-3.5%). 3,27,41,42 Reports that fewer colony forming units of bacteria are required to produce surgical site infection in the presence of suture material date back to 1957. 43 It is as a result of this understanding that triclosancoated sutures were developed, with the expectation that asepsis may reduce the number of colony forming units able to grow.…”

Section: Discussionmentioning

confidence: 99%

“…Thirty-one studies (summarised in Table 1) were identified that were appropriate in their question and SURGERY IN GENERAL Table 1 Author quality. These included studies investigating polyglactin, 1,4,[6][7][8][9][10][11][12][13][14] polydioxanone (PDS), 5,[15][16][17][18][19][20][21][22][23][24][25][26][27] polypropylene, 28,29 nylon, [30][31][32] polyglycolic acid (PGA), 33 polyglyconate, triclosan-coated polyglactin, triclosan-coated polydioxanone, Ethibond®, steel, poly(L-lactide-co-glycolide) (PLG) and Polysorb®.…”

Section: Introductionmentioning

confidence: 99%

Suture choice to reduce occurrence of surgical site infection, hernia, wound dehiscence and sinus/fistula: a network meta-analysis

Simillis

Tekkis

et al. 2019

annals

View full text Add to dashboard Cite

Background There are many options and little guiding evidence when choosing suture types with which to close the abdominal wall fascia. This network meta-analysis investigated the effect of suture materials on surgical site infection, hernia, wound dehiscence and sinus/fistula occurrence after abdominal surgery. The aim was to provide clarity on whether previous recommendations on suture choice could be followed with confidence. Methods and methods In February 2017, the Cochrane Central Register of Controlled Trials, Medline, EMBASE and Science Citation Index Expanded were searched for randomised controlled trials investigating the effect of suture choice on these four complications in closing the abdomen. A reference search of identified trials was performed. Prisma guidelines and the Cochrane risk of bias tool were followed in the data extraction and synthesis. Two review authors screened titles and abstracts of trials identified. A random effect model was used for the surgical site infection network based on the deviance information criterion statistics. Results Thirty-one trials were included (11,533 participants). No suture material reached the predetermined 90% probability threshold for determination of ‘best treatment’ for any outcome. Pairwise comparisons largely showed no differences between suture types for all outcomes measured. However, nylon demonstrated a reduction in the occurrence of incisional hernias with respect to two commonly used absorbable sutures: polyglycolic acid (odds ratio, OR 1.91; 95% confidence interval, CI, 1.01–3.63) and polyglyconate (OR 2.18; 95% CI 1.17–4.07). Conclusions No suture type can be considered the ‘best treatment’ for the prevention of surgical site infection, hernia, wound dehiscence and sinus/fistula occurrence.

show abstract

A Comparative Study of Polydioxanone and Nylon for Abdominal Wall Closure With Interrupted Figure of Eight in Peritonitis Cases

Cited by 4 publications

References 12 publications

Which suture is ideal for abdominal fascial closure: polydioxanone or polypropylene?

Which suture is ideal for abdominal fascial closure: polydioxanone or polypropylene?

Pyridine as an additive to improve the deposition of continuous electrospun filaments

Suture choice to reduce occurrence of surgical site infection, hernia, wound dehiscence and sinus/fistula: a network meta-analysis

Contact Info

Product

Resources

About