A Comparative Study of the Efficacy and Safety of Oral Misoprostol, Intravenous Oxytocin, and Intravaginal Dinoprostone for Labor Induction in Pakistani Women

Wasim, Asad Ullah; Khan, Muhammad Muneeb; LNU, Aneela; Khan, Haris; Solís, Mirna Denise Díaz; Shabir, Insha; Hassan, Syed Saem Ul; Tariq, Umer Bin

doi:10.7759/cureus.39768

Cureus

2023

DOI: 10.7759/cureus.39768

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A Comparative Study of the Efficacy and Safety of Oral Misoprostol, Intravenous Oxytocin, and Intravaginal Dinoprostone for Labor Induction in Pakistani Women

Asad Ullah Wasim,

Muhammad Muneeb Khan,

Aneela LNU

et al.

Abstract: Introduction: A frequent medical procedure to accelerate labor is the induction of labor. There are different methods of labor induction, including the use of medications such as misoprostol, oxytocin, and dinoprostone.

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2024

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Transperineal sonographic assessment of the angle of progression before the onset of labour: how well does it predict the mode of delivery in late-term pregnancy

Güner,

Barut,

Okcu

2024

Journal of Perinatal Medicine

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Objectives Predicting the success of vaginal delivery is an important issue in preventing adverse maternal and neonatal outcomes. This study sought to examine whether measurement of the angle of progression (AoP) can predict a successful vaginal delivery following induction of labour (IoL) among late term nulliparous women with a low (4>) Bishop score. Methods This prospective study included consecutive nulliparous pregnant women whose gestational age was 41 weeks and 1–6 days (late-term). The AoP was measured at least three times and their means were calculated. Results During the study period, data of 150 women were included in the final analysis. Thirty-eight women underwent CS due to failure to progress (n=30) or NRGHR (n=8), while the remaining 112 women underwent NVD, with four women requiring vacuum extraction. The two groups were similar with respect to age, gestational age, BMI, estimated foetal weight, and birth weight. Women undergoing NVD differed significantly from those undergoing CS with respect to a greater ultrasonographic AoP (113.8±11.9° vs. 98.1±10.9°, p=0.0001), a shorter duration of dinoprostone use, shorter time to labour contraction, and a shorter duration of labour. In ROC analysis, the cut-off value for AoP was 100° for the prediction of successful IoL for NVD, with a sensitivity of 96 % and a specificity of 63 %. Conclusions AoP may be a useful sonographic parameter for predicting successful vaginal delivery among nulliparous women at late term undergoing IoL; an AOP wider than 100° is associated with a high rate of vaginal delivery.

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Transperineal sonographic assessment of the angle of progression before the onset of labour: how well does it predict the mode of delivery in late-term pregnancy

Güner,

Barut,

Okcu

2024

Journal of Perinatal Medicine

View full text Add to dashboard Cite

show abstract

Oral Misoprostol vs Intravaginal Dinoprostone for Pre-Induction Cervical Ripening in Post-Term, Uncomplicated Pregnancies: A Randomized Controlled Trial

Godakandage,

Furukan

2024

OJOG

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A Comparative Study of the Efficacy and Safety of Oral Misoprostol, Intravenous Oxytocin, and Intravaginal Dinoprostone for Labor Induction in Pakistani Women

Abstract: Introduction: A frequent medical procedure to accelerate labor is the induction of labor. There are different methods of labor induction, including the use of medications such as misoprostol, oxytocin, and dinoprostone.

Cited by 2 publications

References 18 publications

Transperineal sonographic assessment of the angle of progression before the onset of labour: how well does it predict the mode of delivery in late-term pregnancy

Transperineal sonographic assessment of the angle of progression before the onset of labour: how well does it predict the mode of delivery in late-term pregnancy

Oral Misoprostol vs Intravaginal Dinoprostone for Pre-Induction Cervical Ripening in Post-Term, Uncomplicated Pregnancies: A Randomized Controlled Trial

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