A comparative study of the electrochemical characteristics and simultaneous determination of dopamine, acetaminophen, and aspirin at a ruthenium oxide nanoparticles modified glassy carbon electrode versus a bare one

Chatraei, Fatemeh; Zare, Hamid R.

doi:10.1039/c2ay25402f

Cited by 12 publications

(7 citation statements)

References 63 publications

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“…Sample 4 has an anodic peak which was slightly more positive than that of clopidogrel and was a much broader peak. Previous studies have shown that on a bare glassy carbon electrode aspirin oxidation is observed around 0.97 V, which is in the same vicinity where clopidogrel was measured 34 . With 100 mg of aspirin present within this tablet, the peak amplitude was still lower and would have flagged this sample as a falsified tablet, however this response highlights that any substance that could be oxidised at this voltage with similar peak features of clopidogrel could provide a false positive result and limit the suitability of voltammetry.…”

Section: Validation Studies Using Prepared Substandard and Falsified Clopidogrelsupporting

confidence: 66%

Detection of falsified clopidogrel in the presence of excipients using voltammetry

2021

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Section: Validation Studies Using Prepared Substandard and Falsified Clopidogrelsupporting

confidence: 66%

Detection of falsified clopidogrel in the presence of excipients using voltammetry

2021

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“…Neurotransmitters like dopamine and epinephrine can be detected by direct reaction with an electrode and often do not require the employment of enzymes 70, 71. Simultaneous detection of dopamine and other analytes has become an increasing phenomenon 72, 73 as compared to the sole determination of dopamine 74. To determine dopamine concentrations only, Qiu et al.…”

Section: Analysis Of Other Small Moleculesmentioning

confidence: 99%

Metal Oxide Nanoparticles in Electroanalysis

Lim

Gao

2015

Electroanalysis

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Many important technological advances have been made in the use of nanotechnology in electroanalysis in recent years. Coupled with the development of electroanalytical techniques for the detection of a wide variety of analytes, a lot of effort has been put into realizing accurate, sensitive, selective, and robust electrochemical assays and sensing devices for both laboratory and point‐of‐care applications. The use of metal oxide nanoparticles, in particular, has led to improvements in sensitivity, selectivity, and multiplexing capacity for the analysis of proteins, nucleic acids, as well as small molecules such as glucose and hydrogen peroxide. This article reviews the progress in the research and development of metal oxide nanoparticle‐based electroanalytical methods with an emphasis on their mechanism, performance and applications together with some discussion on challenges and perspectives in this exciting field.

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“…DA also controls the stress level. Loss of DA leads to various brain disorder diseases like parkinsonism, Huntington's disease, Alzheimer's, Schizophrenia [8][9][10]. Hence there is a demand for simultaneous and selective determination of DA and PA in biological fluids.…”

Section: Introductionmentioning

confidence: 99%

A Facile Fabrication of Poly‐ethionine Film on Glassy Carbon Electrode for Simultaneous and Sensitive Detection of Dopamine and Paracetamol

Kannan¹,

Seenivasan

Radhakrishnan

2021

Electroanalysis

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An electrochemical sensor based on poly‐ethionine (Poly‐ET) film modified glassy carbon electrode was developed for sensitive and simultaneous sensing of dopamine (DA) and paracetamol (PA). The electropolymerization of ethionine monomer was carried out to modify the electrode. The modified electrode was characterized by using scanning electron microscopy, cyclic voltammetry and electrochemical impedance spectroscopy. The Poly‐ET/GCE exhibited excellent electrocatalysis towards the sensing of DA and PA. Poly‐ET/GCE showed a linear increase of current response with increase concentration of DA and PA ranging from 0.1 μM–60 μM and 0.1 μM–180 μM, respectively. The LODs were found to be 7 nM and 18 nM (S/N=3) for DA and PA, respectively. This electrochemical sensor was successfully utilized for the detection of DA and PA in pharmaceutical samples.

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A comparative study of the electrochemical characteristics and simultaneous determination of dopamine, acetaminophen, and aspirin at a ruthenium oxide nanoparticles modified glassy carbon electrode versus a bare one

Cited by 12 publications

References 63 publications

Detection of falsified clopidogrel in the presence of excipients using voltammetry

Detection of falsified clopidogrel in the presence of excipients using voltammetry

Metal Oxide Nanoparticles in Electroanalysis

A Facile Fabrication of Poly‐ethionine Film on Glassy Carbon Electrode for Simultaneous and Sensitive Detection of Dopamine and Paracetamol

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