A Comparative Study of Various Metabolic Parameters and Insulin Secretion in Overweight and Obese Individuals

Abstract

BACKGROUND Overweight and obesity are major health issues. As per WHO definition, BMI equal to or greater than 25 is overweight and BMI equal to or greater than 30 is obesity. It is associated with various metabolic physiological abnormalities like changes in insulin secretion and metabolic parameters. MATERIAL AND METHOD Forty individuals were selected for study as per inclusion and exclusion criteria and divided in two groups. All the parameters of both the groups were calculated. RESULT Fasting and postprandial insulin level was normal in overweight individuals, but it was towards higher side in obese that is 25 mIU/L and 176.48 mIU/L. Plasma glucose concentration was normal, but lipid profile was higher in both groups. CONCLUSION Overweight and obesity is now a global issue. It is associated with various physiological abnormalities leading to diabetes mellitus and cardiovascular diseases. Present study is designed to study the effect of overweight and obesity on various parameters in coastal Andhra Pradesh, and it was found that all the parameters in both the groups were towards higher side except few.